Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval.

by Emily A King, J Wade Davis, Jacob F Degner
Published 2019-12-01

Estimating colocalization probability from limited summary statistics

by Emily A. King, Fengjiao Dunbar, Justin Wade Davis, Jacob F. Degner
Published 2021-05-01

Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels.

by Nicholas E Banovich, Xun Lan, Graham McVicker, Bryce van de Geijn, Jacob F Degner, John D Blischak, Julien Roux, Jonathan K Pritchard, Yoav Gilad
Published 2014-09-01

The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels.

by Athma A Pai, Carolyn E Cain, Orna Mizrahi-Man, Sherryl De Leon, Noah Lewellen, Jean-Baptiste Veyrieras, Jacob F Degner, Daniel J Gaffney, Joseph K Pickrell, Matthew Stephens, Jonathan K Pritchard, Yoav Gilad
Published 2012-01-01