Understanding Podocyte Biology to Develop Novel Kidney Therapeutics

by Mark A. Lal, Jaakko Patrakka
Published 2018-07-01

Neph1 Is Reduced in Primary Focal Segmental Glomerulosclerosis, Minimal Change Nephrotic Syndrome, and Corresponding Experimental Animal Models of Adriamycin-Induced Nephropathy an...

by Jenny Hulkko, Jaakko Patrakka, Mark Lal, Karl Tryggvason, Kjell Hultenby, Annika Wernerson
Published 2014-09-01

Wtip- and gadd45a-interacting protein dendrin is not crucial for the development or maintenance of the glomerular filtration barrier.

by Zhijie Xiao, Patricia Q Rodriguez, Liqun He, Christer Betsholtz, Karl Tryggvason, Jaakko Patrakka
Published 2013-01-01

Association of crumbs homolog-2 with mTORC1 in developing podocyte.

by Sho Hamano, Yukino Nishibori, Ichiro Hada, Naoaki Mikami, Noriko Ito-Nitta, Daisuke Fukuhara, Akihiko Kudo, Zhijie Xiao, Masatoshi Nukui, Jaakko Patrakka, Karl Tryggvason, Kunimasa Yan
Published 2018-01-01

Schip1 is a novel podocyte foot process protein that mediates actin cytoskeleton rearrangements and forms a complex with Nherf2 and ezrin.

by Ljubica Perisic, Patricia Q Rodriguez, Kjell Hultenby, Ying Sun, Mark Lal, Christer Betsholtz, Mathias Uhlén, Annika Wernerson, Ulf Hedin, Timo Pikkarainen, Karl Tryggvason, Jaakko Patrakka
Published 2015-01-01

Correction: Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin.

by Ljubica Perisic, Patricia Q Rodriguez, Kjell Hultenby, Ying Sun, Mark Lal, Christer Betsholtz, Mathias Uhlén, Annika Wernerson, Ulf Hedin, Timo Pikkarainen, Karl Tryggvason, Jaakko Patrakka
Published 2015-01-01

Myo1e impairment results in actin reorganization, podocyte dysfunction, and proteinuria in zebrafish and cultured podocytes.

by Jianhua Mao, Dayan Wang, Parikka Mataleena, Bing He, Dadi Niu, Kan Katayama, Xiangjun Xu, Juha Rm Ojala, Wenjing Wang, Qiang Shu, Lizhong Du, Aimin Liu, Timo Pikkarainen, Jaakko Patrakka, Karl Tryggvason
Published 2013-01-01

Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes

by Bing He, Ping Chen, Sonia Zambrano, Dina Dabaghie, Yizhou Hu, Katja Möller-Hackbarth, David Unnersjö-Jess, Gül Gizem Korkut, Emmanuelle Charrin, Marie Jeansson, Maria Bintanel-Morcillo, Anna Witasp, Lars Wennberg, Annika Wernerson, Bernhard Schermer, Thomas Benzing, Patrik Ernfors, Christer Betsholtz, Mark Lal, Rickard Sandberg, Jaakko Patrakka
Published 2021-04-01