Antioxidant Capacities and Analysis of Phenolic Compounds in Three Endemic Nolana Species by HPLC-PDA-ESI-MS

by Mario J. Simirgiotis, Julio Benites, Carlos Areche, Beatriz Sepúlveda
Published 2015-06-01

Inhibition of Escherichia coli and Bacillus subtilis FtsZ Polymerization and Bacillus subtilis Growth by Dihydroxynaphtyl Aryl Ketones

by Gissela Araya, Julio Benites, Julio Benites, Juan S. Reyes, Andrés E. Marcoleta, Jaime A. Valderrama, Jaime A. Valderrama, Rosalba Lagos, Octavio Monasterio
Published 2019-06-01

Access to New Cytotoxic Quinone-Amino Acid Conjugates Linked through A Vinylic Spacer from 2-Acylnaphthoquinones and Methyl 3-Aminocrotonate

by Jaime A. Valderrama, Joel Garrido, Virginia Delgado, Julio Benites, Cristina Theoduloz
Published 2017-12-01

In Vitro Inhibition of Hsp90 Protein by Benzothiazoloquinazolinequinones Is Enhanced in The Presence of Ascorbate. A Preliminary In Vivo Antiproliferative Study

by Jaime A. Valderrama, David Ríos, Giulio G. Muccioli, Pedro Buc Calderon, Julio Benites
Published 2020-02-01

Synthesis and Antitumor Evaluation of 6-Aryl-substituted benzo[j]phenanthridine- and Benzo[g]pyrimido[4,5-c]isoquinolinequinones

by Jennyfer Iribarra, David Vásquez, Cristina Theoduloz, Julio Benites, David Ríos, Jaime A. Valderrama
Published 2012-09-01

Oxidative phenylamination of 5-substituted 1-hydroxynaphthalenes to N-phenyl-1,4-naphthoquinone monoimines by air and light “on water”

by Julio Benites, Juan Meléndez, Cynthia Estela, David Ríos, Luis Espinoza, Iván Brito, Jaime A. Valderrama
Published 2014-10-01

A Review of the Actions of Endogenous and Exogenous Vasoactive Substances during the Estrous Cycle and Pregnancy in Rats

by Luisauris Jaimes, Raúl Vinet, Marcela Knox, Bernardo Morales, Julio Benites, Claudio Laurido, José L. Martínez
Published 2019-05-01

Effects of two bisbenzylisoquinoline alkaloids, Antioquine and Tetrandrine, compared to Verapamil in Rat Thoracic Aorta

by JOSÉ L. MARTINEZ, JULIO BENITES, HAROLD GOMEZ, SILVIA VARGAS-RUEDA, RAÚL VINET, LUISAURIS JAIMES, CLAUDIO LAURIDO

In Vitro Inhibition of Helicobacter pylori Growth by Redox Cycling Phenylaminojuglones

by Julio Benites, Héctor Toledo, Felipe Salas, Angélica Guerrero, David Rios, Jaime A. Valderrama, Pedro Buc Calderon
Published 2018-01-01

Synthesis, Half-Wave Potentials and Antiproliferative Activity of 1-Aryl-substituted Aminoisoquinolinequinones

by Juana Andrea Ibacache, Virginia Delgado, Julio Benites, Cristina Theoduloz, Verónica Arancibia, Giulio G. Muccioli, Jaime A. Valderrama
Published 2014-01-01

Eco-Friendly Synthesis and Antiproliferative Evaluation of Some Oxygen Substituted Diaryl Ketones

by Jaime A. Valderrama, Pedro Buc Calderon, Giulio G. Muccioli, Paola Arenas, Andrés Peña, David Ríos, Julio Benites
Published 2013-08-01

Synthesis and Cytotoxic Activity on Human Cancer Cells of Novel Isoquinolinequinone–Amino Acid Derivatives

by Jaime A. Valderrama, Virginia Delgado, Sandra Sepúlveda, Julio Benites, Cristina Theoduloz, Pedro Buc Calderon, Giulio G. Muccioli
Published 2016-09-01

Seco-Taondiol, an Unusual Meroterpenoid from the Chilean Seaweed Stypopodium flabelliforme and Its Gastroprotective Effect in Mouse Model

by Carlos Areche, Julio Benites, Alberto Cornejo, Lina M. Ruiz, Olimpo García-Beltrán, Mario J. Simirgiotis, Beatriz Sepúlveda
Published 2015-03-01

Half-Wave Potentials and In Vitro Cytotoxic Evaluation of 3-Acylated 2,5-<i>Bis</i>(phenylamino)-1,4-benzoquinones on Cancer Cells

by Julio Benites, Jaime A. Valderrama, Maryan Ramos, Maudy Valenzuela, Angélica Guerrero-Castilla, Giulio G. Muccioli, Pedro Buc Calderon
Published 2019-05-01

New 2-Acetyl-3-aminophenyl-1,4-naphthoquinones: Synthesis and In Vitro Antiproliferative Activities on Breast and Prostate Human Cancer Cells

by David Ríos, Jaime A. Valderrama, Miriam Cautin, Milko Tapia, Felipe Salas, Angélica Guerrero-Castilla, Giulio G. Muccioli, Pedro Buc Calderón, Julio Benites
Published 2020-01-01

Ascorbate Attenuates Oxidative Stress and Increased Blood Pressure Induced by 2-(4-Hydroxyphenyl) Amino-1,4-naphthoquinone in Rats

by Javier Palacios, José Miguel Fonseca, Fernando Ayavire, Felipe Salas, Mirko Ortiz, Juan Marcelo Sandoval, Julio Benites, Chukwuemeka R. Nwokocha, Ewaldo Zavala, Adrián Paredes, Iván Barría, José Luis Vega, Fredi Cifuentes
Published 2018-01-01

Modulatory Effect of 2-(4-Hydroxyphenyl)amino-1,4-naphthoquinone on Endothelial Vasodilation in Rat Aorta

by Javier Palacios, Fredi Cifuentes, Jaime A. Valderrama, Julio Benites, David Ríos, Constanza González, Mario Chiong, Benjamín Cartes-Saavedra, Carlos Lafourcade, Ursula Wyneken, Pamela González, Gareth I. Owen, Fabián Pardo, Luis Sobrevia, Pedro Buc Calderon
Published 2016-01-01

DNA Damage and Inhibition of Akt Pathway in MCF-7 Cells and Ehrlich Tumor in Mice Treated with 1,4-Naphthoquinones in Combination with Ascorbate

by Fabiana Ourique, Maicon R. Kviecinski, Karina B. Felipe, João Francisco Gomes Correia, Mirelle S. Farias, Luiza S. E. P. W. Castro, Valdelúcia M. A. S. Grinevicius, Jaime Valderrama, David Rios, Julio Benites, Pedro Buc Calderon, Rozangela Curi Pedrosa
Published 2015-01-01