ROLE of IGF-1 System in the Modulation of Longevity: Controversies and New Insights From a Centenarians' Perspective

by Giovanni Vitale, Giovanni Vitale, Giuseppe Pellegrino, Maria Vollery, Leo J. Hofland
Published 2019-02-01

Evaluation of Spheroid 3D Culture Methods to Study a Pancreatic Neuroendocrine Neoplasm Cell Line

by Giulia Bresciani, Leo J. Hofland, Fadime Dogan, Georgios Giamas, Teresa Gagliano, Maria Chiara Zatelli
Published 2019-10-01

Prospective methods for identifying perioperative risk‐assessment methods for patient safety over 20 years: a systematic review

by A. J. Heideveld‐Chevalking, H. Calsbeek, J. Hofland, W. J. H. J. Meijerink, A. P. Wolff
Published 2020-04-01

Interferon-Gamma DNA Methylation Is Affected by Mycophenolic Acid but Not by Tacrolimus after T-Cell Activation

by Fleur S. Peters, Annemiek M. A. Peeters, Leo J. Hofland, Michiel G. H. Betjes, Karin Boer, Carla C. Baan
Published 2017-07-01

Potency of Full-Length MGF to Induce Maximal Activation of the IGF-I R Is Similar to Recombinant Human IGF-I at High Equimolar Concentrations.

by Joseph A M J L Janssen, Leo J Hofland, Christian J Strasburger, Elisabeth S R van den Dungen, Mario Thevis
Published 2016-01-01

The role of mTOR pathway as target for treatment in adrenocortical cancer

by Maria Cristina De Martino, Richard A Feelders, Claudia Pivonello, Chiara Simeoli, Fortuna Papa, Annamaria Colao, Rosario Pivonello, Leo J Hofland
Published 2019-09-01

How to Differentiate Benign from Malignant Adrenocortical Tumors?

by Charlotte L. Viëtor, Sara G. Creemers, Folkert J. van Kemenade, Tessa M. van Ginhoven, Leo J. Hofland, Richard A. Feelders
Published 2021-08-01

Temozolomide-Induced Shrinkage of a Pituitary Carcinoma Causing Cushing's Disease — Report of a Case and Literature Review

by Lorenzo Curtò, Maria L. Torre, Francesco Ferraù, Vincenzo Pitini, Giuseppe Altavilla, Francesca Granata, Marcello Longo, Leo J. Hofland, Francesco Trimarchi, Salvatore Cannavò
Published 2010-01-01

Interferon-beta enhances sensitivity to gemcitabine in pancreatic cancer

by Amber Blaauboer, Stephanie Booy, Peter M. van Koetsveld, Bas Karels, Fadime Dogan, Suzanne van Zwienen, Casper H. J. van Eijck, Leo J. Hofland
Published 2020-09-01

Successful neoadjuvant peptide receptor radionuclide therapy for an inoperable pancreatic neuroendocrine tumour

by Tiago Nunes da Silva, (Loes) M L F van Velthuysen, Casper H J van Eijck, Jaap J Teunissen, (Hans) J Hofland, Wouter W de Herder
Published 2018-04-01

Vandetanib versus Cabozantinib in Medullary Thyroid Carcinoma: A Focus on Anti-Angiogenic Effects in Zebrafish Model

by Silvia Carra, Germano Gaudenzi, Alessandra Dicitore, Davide Saronni, Maria Celeste Cantone, Alice Plebani, Anna Ghilardi, Maria Orietta Borghi, Leo J. Hofland, Luca Persani, Giovanni Vitale
Published 2021-03-01

Modifying Effects of Glucose and Insulin/Insulin-Like Growth Factors on Colon Cancer Cells

by Şeyda Berk, Şeyda Berk, Joseph A. M. J. L. Janssen, Peter M. van Koetsveld, Fadime Dogan, Naci Değerli, Servet Özcan, Servet Özcan, Fahrettin Kelestimur, Fahrettin Kelestimur, Leo J. Hofland
Published 2021-07-01

Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer

by Fleur S. Peters, Annemiek M. A. Peeters, Pooja R. Mandaviya, Joyce B. J. van Meurs, Leo J. Hofland, Jacqueline van de Wetering, Michiel G. H. Betjes, Carla C. Baan, Karin Boer
Published 2018-06-01

Inhibin alpha-subunit (INHA) expression in adrenocortical cancer is linked to genetic and epigenetic INHA promoter variation.

by Johannes Hofland, Jacobie Steenbergen, Jacoba M Voorsluijs, Michael M P J Verbiest, Ronald R de Krijger, Leo J Hofland, Wouter W de Herder, Andre G Uitterlinden, Richard A Feelders, Frank H de Jong
Published 2014-01-01

Peptide receptor radionuclide therapy in patients with medullary thyroid carcinoma: predictors and pitfalls

by Carolien M. Beukhof, Tessa Brabander, Francien H. van Nederveen, Marie-Louise F. van Velthuysen, Yolanda B. de Rijke, Leo J. Hofland, Gaston J. H. Franssen, Lideke A. C. Fröberg, Boen L. R. Kam, W. Edward Visser, Wouter W. de Herder, Robin P. Peeters
Published 2019-04-01

Somatostatin analogues for receptor targeted photodynamic therapy.

by Slávka Kaščáková, Leo J Hofland, Henriette S De Bruijn, Yunpeng Ye, Samuel Achilefu, Katy van der Wansem, Angelique van der Ploeg-van den Heuvel, Peter M van Koetsveld, Michael P Brugts, Aart-Jan van der Lelij, Henricus J C M Sterenborg, Timo L M Ten Hagen, Dominic J Robinson, Martin P van Hagen
Published 2014-01-01