Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function.

by Megan T Harris, Syed Saad Hussain, Candice M Inouye, Anna M Castle, J David Castle
Published 2018-01-01

Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function.

by Brittany A Martínez, Rosalie G Hoyle, Scott Yeudall, Mitchell E Granade, Thurl E Harris, J David Castle, Norbert Leitinger, Michelle L Bland
Published 2020-11-01

In vitro fusion of single synaptic and dense core vesicles reproduces key physiological properties

by Alex J. B. Kreutzberger, Volker Kiessling, Christopher Stroupe, Binyong Liang, Julia Preobraschenski, Marcelo Ganzella, Mark A. B. Kreutzberger, Robert Nakamoto, Reinhard Jahn, J. David Castle, Lukas K. Tamm
Published 2019-08-01

Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2

by Alex J B Kreutzberger, Volker Kiessling, Catherine A Doyle, Noah Schenk, Clint M Upchurch, Margaret Elmer-Dixon, Amanda E Ward, Julia Preobraschenski, Syed S Hussein, Weronika Tomaka, Patrick Seelheim, Iman Kattan, Megan Harris, Binyong Liang, Anne K Kenworthy, Bimal N Desai, Norbert Leitinger, Arun Anantharam, J David Castle, Lukas K Tamm
Published 2020-11-01