Hypoxia-Induced Energy Stress Inhibits the mTOR Pathway by Activating an AMPK/REDD1 Signaling Axis in Head and Neck Squamous Cell Carcinoma

by Abraham Schneider, Rania H. Younis, J. Silvio Gutkind
Published 2008-11-01

Circulating Fibroblast Growth Factor-2, HIV-Tat, and Vascular Endothelial Cell Growth Factor-A in HIV-Infected Children with Renal Disease Activate Rho-A and Src in Cultured Renal...

by Jharna R Das, J Silvio Gutkind, Patricio E Ray
Published 2016-01-01

Binding-induced folding of a natively unstructured transcription factor.

by Adrian Gustavo Turjanski, J Silvio Gutkind, Robert B Best, Gerhard Hummer
Published 2008-04-01

Accelerated wound healing by mTOR activation in genetically defined mouse models.

by Cristiane H Squarize, Rogerio M Castilho, Thomas H Bugge, J Silvio Gutkind
Published 2010-05-01

436 Rational sequencing of immune-oncology therapies achieves durable response and immunologic memory

by Robert Saddawi-Konefka, Aoife O’Farrell, Andrew Sharabi, Joseph Califano, J Silvio Gutkind
Published 2020-11-01

Rac1 is required for epithelial stem cell function during dermal and oral mucosal wound healing but not for tissue homeostasis in mice.

by Rogerio M Castilho, Cristiane H Squarize, Kantima Leelahavanichkul, Yi Zheng, Thomas Bugge, J Silvio Gutkind
Published 2010-05-01

Nano Delivers Big: Designing Molecular Missiles for Cancer Therapeutics

by J. Silvio Gutkind, Vyomesh Patel, Xiaoyuan Chen, Ashwin A. Bhirde, James F. Rusling, Sachin Patel
Published 2011-01-01

Development and optimization of orthotopic liver metastasis xenograft mouse models in uveal melanoma

by Takahito Sugase, Bao Q. Lam, Meggie Danielson, Mizue Terai, Andrew E. Aplin, J. Silvio Gutkind, Takami Sato
Published 2020-05-01

PTEN Deficiency Contributes to the Development and Progression of Head and Neck Cancer

by Cristiane H Squarize, Rogerio M Castilho, Aline C Abrahao, Alfredo Molinolo, Mark W Lingen, J Silvio Gutkind
Published 2013-05-01

Correction: Rigiracciolo, D.C., et al., IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells. <i>Cells</i> 2020, 9, 1010

by Damiano Cosimo Rigiracciolo, Nijiro Nohata, Rosamaria Lappano, Francesca Cirillo, Marianna Talia, Domenica Scordamaglia, J. Silvio Gutkind, Marcello Maggiolini
Published 2020-12-01

IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells

by Damiano Cosimo Rigiracciolo, Nijiro Nohata, Rosamaria Lappano, Francesca Cirillo, Marianna Talia, Domenica Scordamaglia, J. Silvio Gutkind, Marcello Maggiolini
Published 2020-04-01

Improved Clearance during Treatment of HPV-Positive Head and Neck Cancer through mTOR Inhibition

by Joseph D. Coppock, Bryant G. Wieking, Alfredo A. Molinolo, J. Silvio Gutkind, W. Keith Miskimins, John H. Lee
Published 2013-06-01

G protein-regulated endocytic trafficking of adenylyl cyclase type 9

by André M Lazar, Roshanak Irannejad, Tanya A Baldwin, Aparna B Sundaram, J Silvio Gutkind, Asuka Inoue, Carmen W Dessauer, Mark Von Zastrow
Published 2020-06-01

Epidermal loss of Gαq confers a migratory and differentiation defect in keratinocytes.

by Colleen L Doçi, Constantinos M Mikelis, Juan Luis Callejas-Valera, Karina K Hansen, Alfredo A Molinolo, Asuka Inoue, Stefan Offermanns, J Silvio Gutkind
Published 2017-01-01

Combining Portable Raman Probes with Nanotubes for Theranostic Applications

by Ashwinkumar A. Bhirde, Gang Liu, Albert Jin, Ramiro Iglesias-Bartolome, Alioscka A. Sousa, Richard D. Leapman, J. Silvio Gutkind, Seulki Lee, Xiaoyuan Chen
Published 2011-01-01

LKB1/AMPK and PKA control ABCB11 trafficking and polarization in hepatocytes.

by László Homolya, Dong Fu, Prabuddha Sengupta, Michal Jarnik, Jean-Pierre Gillet, Lynn Vitale-Cross, J Silvio Gutkind, Jennifer Lippincott-Schwartz, Irwin M Arias
Published 2014-01-01

Longitudinal imaging studies of tumor microenvironment in mice treated with the mTOR inhibitor rapamycin.

by Keita Saito, Shingo Matsumoto, Hironobu Yasui, Nallathamby Devasahayam, Sankaran Subramanian, Jeeva P Munasinghe, Vyomesh Patel, J Silvio Gutkind, James B Mitchell, Murali C Krishna
Published 2012-01-01

A systems genetics approach identifies CXCL14, ITGAX, and LPCAT2 as novel aggressive prostate cancer susceptibility genes.

by Kendra A Williams, Minnkyong Lee, Ying Hu, Jonathan Andreas, Shashank J Patel, Suiyuan Zhang, Peter Chines, Abdel Elkahloun, Settara Chandrasekharappa, J Silvio Gutkind, Alfredo A Molinolo, Nigel P S Crawford
Published 2014-11-01

Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation.

by Roman Szabo, Katiuchia Uzzun Sales, Peter Kosa, Natalia A Shylo, Sine Godiksen, Karina K Hansen, Stine Friis, J Silvio Gutkind, Lotte K Vogel, Edith Hummler, Eric Camerer, Thomas H Bugge
Published 2012-01-01

Effects of palbociclib on oral squamous cell carcinoma and the role of <i>PIK3CA</i> in conferring resistance

by Nur Syafinaz Zainal, Bernard Kok Bang Lee, Zheng Wei Wong, Iuan Sheau Chin, Pei San Yee, Chai Phei Gan, Kein Seong Mun, Zainal Ariff Abdul Rahman, J. Silvio Gutkind, Vyomesh Patel, Sok Ching Cheong
Published 2019-06-01