Highly pathogenic H5N1 influenza viruses carry virulence determinants beyond the polybasic hemagglutinin cleavage site.

by Jessica Bogs, Jutta Veits, Sandra Gohrbandt, Jana Hundt, Olga Stech, Angele Breithaupt, Jens P Teifke, Thomas C Mettenleiter, Jürgen Stech
Published 2010-01-01

Characterization of the sialic acid binding activity of influenza A viruses using soluble variants of the H7 and H9 hemagglutinins.

by Anne-Kathrin Sauer, Chi-Hui Liang, Jürgen Stech, Ben Peeters, Pascale Quéré, Christel Schwegmann-Wessels, Chung-Yi Wu, Chi-Huey Wong, Georg Herrler
Published 2014-01-01

Neuraminidase-associated plasminogen recruitment enables systemic spread of natural avian Influenza viruses H3N1.

by Jacob Schön, Angele Breithaupt, Dirk Höper, Jacqueline King, Anne Pohlmann, Rokshana Parvin, Klaus-Peter Behr, Bernd-Andreas Schwarz, Martin Beer, Jürgen Stech, Timm Harder, Christian Grund
Published 2021-04-01

A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle

by Scott Martin, Abhilash I. Chiramel, Marie Luisa Schmidt, Yu-Chi Chen, Nadia Whitt, Ari Watt, Eric C. Dunham, Kyle Shifflett, Shelby Traeger, Anne Leske, Eugen Buehler, Cynthia Martellaro, Janine Brandt, Lisa Wendt, Andreas Müller, Stephanie Peitsch, Sonja M. Best, Jürgen Stech, Stefan Finke, Angela Römer-Oberdörfer, Allison Groseth, Heinz Feldmann, Thomas Hoenen
Published 2018-08-01