Testing of drug-induced pseudo-allergies in a porcine model

by Janos Szebeni
Published 2020-08-01

The Critical Choice of Animal Models in Nanomedicine Safety Assessment: A Lesson Learned From Hemoglobin-Based Oxygen Carriers

by Peter Bedőcs, Peter Bedőcs, Peter Bedőcs, János Szebeni, János Szebeni, János Szebeni
Published 2020-10-01

Human Clinical Relevance of the Porcine Model of Pseudoallergic Infusion Reactions

by János Szebeni, Raj Bawa
Published 2020-04-01

Pseudo-anaphylaxis to PEGylated nanomedicines in a porcine model

by Janos Szebeni, Gergely Kozma, Tamas Meszaros, Rudolf Urbanics
Published 2020-08-01

A porcine model of complement activation-related pseudoallergy to nano-pharmaceuticals: Pros and cons of translation to a preclinical safety test

by János Szebeni, Rudolf Urbanics, László Dézsi, Péter Bedőcs

Plasma samples from mouse strains and humans demonstrate different in vitro susceptibilities to complement activation

by Marina Dobrovolskaia, Barry W Neun, Gábor Szénási, János Szebeni

Understanding the Role of Anti-PEG Antibodies in the Complement Activation by Doxil in Vitro

by Barry W. Neun, Yechezkel Barenholz, Janos Szebeni, Marina A. Dobrovolskaia
Published 2018-07-01

Mini-Factor H Modulates Complement-Dependent IL-6 and IL-10 Release in an Immune Cell Culture (PBMC) Model: Potential Benefits Against Cytokine Storm

by Gergely Tibor Kozma, Gergely Tibor Kozma, Tamás Mészáros, Tamás Mészáros, Tamás Bakos, Mark Hennies, Dániel Bencze, Barbara Uzonyi, Balázs Győrffy, Balázs Győrffy, Edward Cedrone, Marina A. Dobrovolskaia, Mihály Józsi, Mihály Józsi, János Szebeni, János Szebeni, János Szebeni
Published 2021-04-01

Infusion Reactions Associated with the Medical Application of Monoclonal Antibodies: The Role of Complement Activation and Possibility of Inhibition by Factor H

by Tamás Fülöp, Tamás Mészáros, Gergely Tibor Kozma, János Szebeni, Mihály Józsi
Published 2018-03-01

Peptide-based Vaccines Derived from FcεRI Beta Subunit Can Reduce Allergic Response in Mice Model

by Ahad Zare, Ali Akbar Pourfathollah, Zahra Pourpak, Janos Szebeni, Seyed Mohammad Reza Ghaffari, Gholam Ali Kardar
Published 2017-08-01

PEGylated liposomes: immunological responses

by Marwa Mohamed, Amr S. Abu Lila, Taro Shimizu, Eman Alaaeldin, Amal Hussein, Hatem A. Sarhan, Janos Szebeni, Tatsuhiro Ishida
Published 2019-12-01

Complement Activation-Related Pathophysiological Changes in Anesthetized Rats: Activator-Dependent Variations of Symptoms and Mediators of Pseudoallergy

by László Dézsi, Tamás Mészáros, Erik Őrfi, Tamás G. Fülöp, Mark Hennies, László Rosivall, Péter Hamar, János Szebeni, Gábor Szénási
Published 2019-09-01

Immunocompatibility of Rad-PC-Rad liposomes in vitro, based on human complement activation and cytokine release

by Bert Müller, Sofiya Matviykiv, Gabriela Gerganova, Tamás Mészáros, Gergely Tibor Kozma, Ute Mettal, Frederik Neuhaus, Takashi Ishikawa, János Szebeni, Andreas Zumbuehl

Anticoagulants Influence the Performance of In Vitro Assays Intended for Characterization of Nanotechnology-Based Formulations

by Edward Cedrone, Barry W. Neun, Jamie Rodriguez, Alison Vermilya, Jeffrey D. Clogston, Scott E. McNeil, Yechezkel Barenholz, Janos Szebeni, Marina A. Dobrovolskaia
Published 2017-12-01

Identification of galectin-1 as a critical factor in function of mouse mesenchymal stromal cell-mediated tumor promotion.

by Gábor János Szebeni, Éva Kriston-Pál, Péter Blazsó, Róbert László Katona, Julianna Novák, Enikő Szabó, Ágnes Czibula, Roberta Fajka-Boja, Beáta Hegyi, Ferenc Uher, László Krenács, Gabriella Joó, Éva Monostori
Published 2012-01-01

Human serum albumin nanoparticles loaded with phthalocyanine dyes for potential use in photodynamic therapy of atherosclerotic plaques

by Shubhadeep Banerjee, Jayeeta Sengupta, Ana Isabel Aljarilla, Francesca Setaro, Petri Makinen, LinPing Wu, Lari Holappa, Andres de la Escosura, Chiara Martinelli, Panagiotis Trohopoulos, Seppo Ylä-Herttuala, Rudolf Urbanics, Janos Szebeni, Tomas Torres, Silke Krol