AAV-mediated Sirt1 overexpression in skeletal muscle activates oxidative capacity but does not prevent insulin resistance

by Laia Vil, Carles Roca, Ivet Elias, Alba Casellas, Ricardo Lage, Sylvie Franckhauser, Fatima Bosch
Published 2016-01-01

AAV8-mediated Sirt1 gene transfer to the liver prevents high carbohydrate diet-induced nonalcoholic fatty liver disease

by Laia Vilà, Ivet Elias, Carles Roca, Albert Ribera, Tura Ferré, Alba Casellas, Ricardo Lage, Sylvie Franckhauser, Fatima Bosch
Published 2014-01-01

BMP4 Gene Therapy in Mature Mice Reduces BAT Activation but Protects from Obesity by Browning Subcutaneous Adipose Tissue

by Jenny M. Hoffmann, John R. Grünberg, Christopher Church, Ivet Elias, Vilborg Palsdottir, John-Olov Jansson, Fatima Bosch, Ann Hammarstedt, Shahram Hedjazifar, Ulf Smith
Published 2017-08-01

Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver.

by Roxana Khatib Shahidi, Jenny M Hoffmann, Shahram Hedjazifar, Laurianne Bonnet, Ritesh K Baboota, Stephanie Heasman, Christopher Church, Ivet Elias, Fatima Bosch, Jeremie Boucher, Ann Hammarstedt, Ulf Smith
Published 2021-01-01

BMP4 gene therapy enhances insulin sensitivity but not adipose tissue browning in obese mice

by Jenny M. Hoffmann, John R. Grünberg, Ann Hammarstedt, Tobias Kroon, Thomas U. Greiner, Stefanie Maurer, Ivet Elias, Vilborg Palsdottir, Fatima Bosch, Jeremie Boucher, Shahram Hedjazifar, Ulf Smith
Published 2020-02-01

Long-Term Efficacy and Safety of Insulin and Glucokinase Gene Therapy for Diabetes: 8-Year Follow-Up in Dogs

by Maria Luisa Jaén, Laia Vilà, Ivet Elias, Veronica Jimenez, Jordi Rodó, Luca Maggioni, Rafael Ruiz-de Gopegui, Miguel Garcia, Sergio Muñoz, David Callejas, Eduard Ayuso, Tura Ferré, Iris Grifoll, Anna Andaluz, Jesus Ruberte, Virginia Haurigot, Fatima Bosch
Published 2017-09-01

FGF21 gene therapy as treatment for obesity and insulin resistance

by Veronica Jimenez, Claudia Jambrina, Estefania Casana, Victor Sacristan, Sergio Muñoz, Sara Darriba, Jordi Rodó, Cristina Mallol, Miquel Garcia, Xavier León, Sara Marcó, Albert Ribera, Ivet Elias, Alba Casellas, Ignasi Grass, Gemma Elias, Tura Ferré, Sandra Motas, Sylvie Franckhauser, Francisca Mulero, Marc Navarro, Virginia Haurigot, Jesus Ruberte, Fatima Bosch
Published 2018-08-01