The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic β-Cells

by Itaru Kojima, Yuko Nakagawa
Published 2011-10-01

Glucose Evokes Rapid Ca2+ and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells.

by Yuko Nakagawa, Masahiro Nagasawa, Johan Medina, Itaru Kojima
Published 2015-01-01

Sweet Taste-Sensing Receptors Expressed in Pancreatic β-Cells: Sweet Molecules Act as Biased Agonists

by Itaru Kojima, Yuko Nakagawa, Yoshiaki Ohtsu, Anya Medina, Masahiro Nagasawa
Published 2014-03-01

Sweet taste receptor serves to activate glucose- and leptin-responsive neurons in the hypothalamic arcuate nucleus and participates in glucose responsiveness.

by Daisuke Kohno, Miho Koike, Yuzo Ninomiya, Itaru Kojima, Tadahiro Kitamura, Toshihiko Yada
Published 2016-11-01

Differentiation of Adult Hepatic Stem-Like Cells into Pancreatic Endocrine Cells

by Satoko Yamada, Kunihiko Terada, Yasuharu Ueno, Toshihiro Sugiyama, Masaharu Seno, Itaru Kojima M.D.
Published 2005-10-01

Correction: T1R3 homomeric sweet taste receptor regulates adipogenesis through Gαs-mediated microtubules disassembly and Rho activation in 3T3-L1 cells.

by Yosuke Masubuchi, Yuko Nakagawa, Johan Medina, Masahiro Nagasawa, Itaru Kojima, Mark M Rasenick, Takeshi Inagaki, Hiroshi Shibata
Published 2017-01-01

T1R3 homomeric sweet taste receptor regulates adipogenesis through Gαs-mediated microtubules disassembly and Rho activation in 3T3-L1 cells.

by Yosuke Masubuchi, Yuko Nakagawa, Johan Medina, Masahiro Nagasawa, Itaru Kojima, Mark M Rasenick, Takeshi Inagaki, Hiroshi Shibata
Published 2017-01-01

A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells.

by Yosuke Masubuchi, Yuko Nakagawa, Jinhui Ma, Tsutomu Sasaki, Tadahiro Kitamura, Yoritsuna Yamamoto, Hitoshi Kurose, Itaru Kojima, Hiroshi Shibata
Published 2013-01-01

Dicer is required for maintaining adult pancreas.

by Sumiyo Morita, Akemi Hara, Itaru Kojima, Takuro Horii, Mika Kimura, Tadahiro Kitamura, Takahiro Ochiya, Katsumi Nakanishi, Ryo Matoba, Kenichi Matsubara, Izuho Hatada
Published 2009-01-01

Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion.

by Yuko Nakagawa, Masahiro Nagasawa, Satoko Yamada, Akemi Hara, Hideo Mogami, Viacheslav O Nikolaev, Martin J Lohse, Noriatsu Shigemura, Yuzo Ninomiya, Itaru Kojima
Published 2009-01-01

Reduced transient receptor potential vanilloid 2 expression in alveolar macrophages causes COPD in mice through impaired phagocytic activity

by Hiroaki Masubuchi, Manabu Ueno, Toshitaka Maeno, Koichi Yamaguchi, Kenichiro Hara, Hiroaki Sunaga, Hiroki Matsui, Masahiro Nagasawa, Itaru Kojima, Yuko Iwata, Shigeo Wakabayashi, Masahiko Kurabayashi
Published 2019-03-01

Follistatin, an Activin Antagonist, Ameliorates Renal Interstitial Fibrosis in a Rat Model of Unilateral Ureteral Obstruction

by Akito Maeshima, Keiichiro Mishima, Shin Yamashita, Masao Nakasatomi, Masaaki Miya, Noriyuki Sakurai, Toru Sakairi, Hidekazu Ikeuchi, Keiju Hiromura, Yoshihisa Hasegawa, Itaru Kojima, Yoshihisa Nojima
Published 2014-01-01