Design of a New α-1-C-Alkyl-DAB Derivative Acting as a Pharmacological Chaperone for β-Glucocerebrosidase Using Ligand Docking and Molecular Dynamics Simulation

by Izumi Nakagome, Atsushi Kato, Noriyuki Yamaotsu, Tomoki Yoshida, Shin-ichiro Ozawa, Isao Adachi, Shuichi Hirono
Published 2018-10-01

Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity

by Atsushi Kato, Izumi Nakagome, Mizuki Hata, Robert J. Nash, George W. J. Fleet, Yoshihiro Natori, Yuichi Yoshimura, Isao Adachi, Shuichi Hirono
Published 2020-06-01

Hepatitis E Virus Outbreak in Monkey Facility, Japan

by Hiroshi Yamamoto, Juri Suzuki, Atsushi Matsuda, Takafumi Ishida, Yasushi Ami, Yuriko Suzaki, Isao Adachi, Takaji Wakita, Naokazu Takeda, Tian-Cheng Li
Published 2012-12-01