Enzymatic synthesis of RNAs capped with nucleotide analogues reveals the molecular basis for substrate selectivity of RNA capping enzyme: impacts on RNA metabolism.

by Moheshwarnath Issur, Isabelle Bougie, Simon Despins, Martin Bisaillon
Published 2013-01-01

Virtual high-throughput screening identifies mycophenolic acid as a novel RNA capping inhibitor.

by Maude Tremblay-Létourneau, Simon Despins, Isabelle Bougie, Martin Bisaillon
Published 2011-01-01

The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme.

by Frédéric Picard-Jean, Isabelle Bougie, Satoshi Shuto, Martin Bisaillon
Published 2013-01-01