Coumarin-Based Triapine Derivatives and Their Copper(II) Complexes: Synthesis, Cytotoxicity and mR2 RNR Inhibition Activity

by Iryna Stepanenko, Maria V. Babak, Gabriella Spengler, Marta Hammerstad, Ana Popovic-Bijelic, Sergiu Shova, Gabriel E. Büchel, Denisa Darvasiova, Peter Rapta, Vladimir B. Arion
Published 2021-06-01

Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells

by Kateryna Ohui, Iryna Stepanenko, Iuliana Besleaga, Maria V. Babak, Radu Stafi, Denisa Darvasiova, Gerald Giester, Vivien Pósa, Eva A. Enyedy, Daniel Vegh, Peter Rapta, Wee Han Ang, Ana Popović-Bijelić, Vladimir B. Arion
Published 2020-09-01