Reassessing the role of APOBEC3G in human immunodeficiency virus type 1 infection of quiescent CD4+ T-cells.

by Masakazu Kamata, Yoshiko Nagaoka, Irvin S Y Chen
Published 2009-03-01

Modeling large fluctuations of thousands of clones during hematopoiesis: The role of stem cell self-renewal and bursty progenitor dynamics in rhesus macaque.

by Song Xu, Sanggu Kim, Irvin S Y Chen, Tom Chou
Published 2018-10-01

Live cell monitoring of hiPSC generation and differentiation using differential expression of endogenous microRNAs.

by Masakazu Kamata, Min Liang, Shirley Liu, Yoshiko Nagaoka, Irvin S Y Chen
Published 2010-07-01

Viruses that affect the immune system

by Hung Y. FAN, Irvin S.Y. CHEN, N. ROSENBERG, William SUGDEN
Published 1992-08-01

Modulation of Gene Expression by Polymer Nanocapsule Delivery of DNA Cassettes Encoding Small RNAs.

by Ming Yan, Jing Wen, Min Liang, Yunfeng Lu, Masakazu Kamata, Irvin S Y Chen
Published 2015-01-01

Specific Elimination of Latently HIV-1 Infected Cells Using HIV-1 Protease-Sensitive Toxin Nanocapsules.

by Jing Wen, Ming Yan, Yang Liu, Jie Li, Yiming Xie, Yunfeng Lu, Masakazu Kamata, Irvin S Y Chen
Published 2016-01-01

High-throughput screening of effective siRNAs using luciferase-linked chimeric mRNA.

by Shen Pang, Lauren Pokomo, Kevin Chen, Masakazu Kamata, Si-Hua Mao, Hong Zhang, Elliot Razi, Dong Sung An, Irvin S Y Chen
Published 2014-01-01

RNAi-Mediated CCR5 Knockdown Provides HIV-1 Resistance to Memory T Cells in Humanized BLT Mice

by Saki Shimizu, Gene-Errol Ringpis, Matthew D Marsden, Ruth V Cortado, Holly M Wilhalme, David Elashoff, Jerome A Zack, Irvin S Y Chen, Dong Sung An
Published 2015-01-01

Robust CAR-T memory formation and function via hematopoietic stem cell delivery.

by Anjie Zhen, Mayra A Carrillo, Wenli Mu, Valerie Rezek, Heather Martin, Philip Hamid, Irvin S Y Chen, Otto O Yang, Jerome A Zack, Scott G Kitchen
Published 2021-04-01

Enhanced Delivery of Rituximab Into Brain and Lymph Nodes Using Timed-Release Nanocapsules in Non-Human Primates

by Meng Qin, Meng Qin, Lan Wang, Lan Wang, Di Wu, Christopher K. Williams, Duo Xu, Emiko Kranz, Emiko Kranz, Qi Guo, Qi Guo, Jiaoqiong Guan, Harry V. Vinters, YooJin Lee, YooJin Lee, Yiming Xie, Yiming Xie, Yun Luo, Guibo Sun, Xiaobo Sun, Zhanlong He, Yunfeng Lu, Masakazu Kamata, Masakazu Kamata, Jing Wen, Jing Wen, Irvin S. Y. Chen, Irvin S. Y. Chen
Published 2020-01-01

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques.

by Jing Wen, Tracy Cheever, Lan Wang, Di Wu, Jason Reed, John Mascola, Xuejun Chen, Cuiping Liu, Amarendra Pegu, Jonah B Sacha, Yunfeng Lu, Nancy L Haigwood, Irvin S Y Chen
Published 2021-07-01

Stem cell–derived CAR T cells traffic to HIV reservoirs in macaques

by Isaac M. Barber-Axthelm, Valerie Barber-Axthelm, Kai Yin Sze, Anjie Zhen, Gajendra W. Suryawanshi, Irvin S.Y. Chen, Jerome A. Zack, Scott G. Kitchen, Hans-Peter Kiem, Christopher W. Peterson
Published 2021-01-01

Modeling Anti-HIV-1 HSPC-Based Gene Therapy in Humanized Mice Previously Infected with HIV-1

by Wannisa Khamaikawin, Saki Shimizu, Masakazu Kamata, Ruth Cortado, Yujin Jung, Jennifer Lam, Jing Wen, Patrick Kim, Yiming Xie, Sanggu Kim, Hubert Arokium, Angela P. Presson, Irvin S.Y. Chen, Dong Sung An
Published 2018-06-01

Longitudinal clonal tracking in humanized mice reveals sustained polyclonal repopulation of gene-modified human-HSPC despite vector integration bias

by Gajendra W. Suryawanshi, Hubert Arokium, Sanggu Kim, Wannisa Khamaikawin, Samantha Lin, Saki Shimizu, Koollawat Chupradit, YooJin Lee, Yiming Xie, Xin Guan, Vasantika Suryawanshi, Angela P. Presson, Dong-Sung An, Irvin S. Y. Chen
Published 2021-10-01

Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice.

by Gene-Errol E Ringpis, Saki Shimizu, Hubert Arokium, Joanna Camba-Colón, Maria V Carroll, Ruth Cortado, Yiming Xie, Patrick Y Kim, Anna Sahakyan, Emily L Lowe, Munetoshi Narukawa, Fadi N Kandarian, Bryan P Burke, Geoff P Symonds, Dong Sung An, Irvin S Y Chen, Masakazu Kamata
Published 2012-01-01

Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.

by Anjie Zhen, Christopher W Peterson, Mayra A Carrillo, Sowmya Somashekar Reddy, Cindy S Youn, Brianna B Lam, Nelson Y Chang, Heather A Martin, Jonathan W Rick, Jennifer Kim, Nick C Neel, Valerie K Rezek, Masakazu Kamata, Irvin S Y Chen, Jerome A Zack, Hans-Peter Kiem, Scott G Kitchen
Published 2017-12-01

Correction: Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.

by Anjie Zhen, Christopher W Peterson, Mayra A Carrillo, Sowmya Somashekar Reddy, Cindy S Youn, Brianna B Lam, Nelson Y Chang, Heather A Martin, Jonathan W Rick, Jennifer Kim, Nick C Neel, Valerie K Rezek, Masakazu Kamata, Irvin S Y Chen, Jerome A Zack, Hans-Peter Kiem, Scott G Kitchen
Published 2018-03-01

Engineering Cellular Resistance to HIV-1 Infection In Vivo Using a Dual Therapeutic Lentiviral Vector

by Bryan P Burke, Bernard R Levin, Jane Zhang, Anna Sahakyan, Joshua Boyer, Maria V Carroll, Joanna Camba Colón, Naomi Keech, Valerie Rezek, Gregory Bristol, Erica Eggers, Ruth Cortado, Maureen P Boyd, Helen Impey, Saki Shimizu, Emily L Lowe, Gene-Errol E Ringpis, Sohn G Kim, Dimitrios N Vatakis, Louis R Breton, Jeffrey S Bartlett, Irvin S Y Chen, Scott G Kitchen, Dong Sung An, Geoff P Symonds
Published 2015-01-01