Glyceraldehyde-3-phosphate Dehydrogenase is a Multifaceted Therapeutic Target

by Vladimir F. Lazarev, Irina V. Guzhova, Boris A. Margulis
Published 2020-05-01

Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates

by Vladimir F. Lazarev, Elena R. Mikhaylova, Irina V. Guzhova, Boris A. Margulis
Published 2017-05-01

Hydrocortisone 21-hemisuccinate did not prevent exogenous GAPDH-induced apoptosis in human neuroblastoma cells

by Vladimir F. Lazarev, Elizaveta A. Dutysheva, Elena Y. Komarova, Irina V. Guzhova, Boris A. Margulis
Published 2018-10-01

Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress

by Marina A. Mikeladze, Elizaveta A. Dutysheva, Victor G. Kartsev, Boris A. Margulis, Irina V. Guzhova, Vladimir F. Lazarev
Published 2021-02-01

Prevention of High Glucose-Mediated EMT by Inhibition of Hsp70 Chaperone

by Alina D. Nikotina, Snezhana A. Vladimirova, Elena Y. Komarova, Dmitry Alexeev, Sergey Efremov, Elizaveta Leonova, Rostislav Pavlov, Viktor G. Kartsev, Sergey G. Polonik, Boris A. Margulis, Irina V. Guzhova
Published 2021-06-01

Etoposide-Induced Apoptosis in Cancer Cells Can Be Reinforced by an Uncoupled Link between Hsp70 and Caspase-3

by Dmitry V. Sverchinsky, Alina D. Nikotina, Elena Y. Komarova, Elena R. Mikhaylova, Nikolay D. Aksenov, Vladimir F. Lazarev, Vladimir A. Mitkevich, Roman Suezov, Dmitry S. Druzhilovskiy, Vladimir V. Poroikov, Boris A. Margulis, Irina V. Guzhova
Published 2018-08-01

Pyrrolylquinoxaline-2-One Derivative as a Potent Therapeutic Factor for Brain Trauma Rehabilitation

by Elizaveta A. Dutysheva, Marina A. Mikeladze, Maria A. Trestsova, Nikolay D. Aksenov, Irina A. Utepova, Elena R. Mikhaylova, Roman V. Suezov, Valery N. Charushin, Oleg N. Chupakhin, Irina V. Guzhova, Boris A. Margulis, Vladimir F. Lazarev
Published 2020-04-01

Properties of substances inhibiting aggregation of oxidized GAPDH: Data on the interaction with the enzyme and the impact on its intracellular content

by Vladimir F. Lazarev, Alina D. Nikotina, Pavel I. Semenyuk, Diana B. Evstafyeva, Elena R. Mikhaylova, Vladimir I. Muronetz, Maxim A. Shevtsov, Anastasia V. Tolkacheva, Anatoly V. Dobrodumov, Alexey L. Shavarda, Irina V. Guzhova, Boris A. Margulis
Published 2016-06-01