Human Blood CD1c+ Dendritic Cells Promote Th1 and Th17 Effector Function in Memory CD4+ T Cells

by Ingrid M. Leal Rojas, Wai-Hong Mok, Frances E. Pearson, Yoshihito Minoda, Tony J. Kenna, Ross T. Barnard, Kristen J. Radford
Published 2017-08-01

Human CD141+ dendritic cells (cDC1) are impaired in patients with advanced melanoma but can be targeted to enhance anti-PD-1 in a humanized mouse model

by Victoria Atkinson, Kelly-Anne Masterman, Ingrid M Leal-Rojas, Frances E Pearson, Kristen J Radford, Yoke Seng Lee, Liam J O'Brien, Carina M Walpole, Andrew Barbour
Published 2021-03-01

Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells

by Frances E Pearson, Kirsteen M Tullett, Ingrid M Leal‐Rojas, Oscar L Haigh, Kelly‐Anne Masterman, Carina Walpole, John S Bridgeman, James E McLaren, Kristin Ladell, Kelly Miners, Sian Llewellyn‐Lacey, David A Price, Antje Tunger, Marc Schmitz, John J Miles, Mireille H Lahoud, Kristen J Radford
Published 2020-01-01