A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease

by Afshan N Malik, Inês C.M. Simões, Hannah S. Rosa, Safa Khan, Agnieszka Karkucinska-Wieckowska, Mariusz R. Wieckowski
Published 2019-10-01

Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response

by Ines C. M. Simoes, Agnieszka Karkucinska-Wieckowska, Justyna Janikiewicz, Sylwia Szymanska, Maciej Pronicki, Pawel Dobrzyn, Michal Dabrowski, Agnieszka Dobrzyn, Paulo J. Oliveira, Hans Zischka, Yaiza Potes, Mariusz R. Wieckowski
Published 2020-10-01

Exploratory Data Analysis of Cell and Mitochondrial High-Fat, High-Sugar Toxicity on Human HepG2 Cells

by Ricardo Amorim, Inês C. M. Simões, Caroline Veloso, Adriana Carvalho, Rui F. Simões, Francisco B. Pereira, Theresa Thiel, Andrea Normann, Catarina Morais, Amália S. Jurado, Mariusz R. Wieckowski, José Teixeira, Paulo J. Oliveira
Published 2021-05-01

The Alterations of Mitochondrial Function during NAFLD Progression—An Independent Effect of Mitochondrial ROS Production

by Inês C. M. Simões, Ricardo Amorim, José Teixeira, Agnieszka Karkucinska-Wieckowska, Adriana Carvalho, Susana P. Pereira, Rui F. Simões, Sylwia Szymanska, Michał Dąbrowski, Justyna Janikiewicz, Agnieszka Dobrzyń, Paulo J. Oliveira, Yaiza Potes, Mariusz R. Wieckowski
Published 2021-06-01