The Role of the Insulin-Like Growth Factor 1 Pathway in Immune Tumor Microenvironment and Its Clinical Ramifications in Gynecologic Malignancies

by Muna Alemi Yahya, Muna Alemi Yahya, Shilhav Meisel Sharon, Shay Hantisteanu, Mordechai Hallak, Mordechai Hallak, Ilan Bruchim, Ilan Bruchim, Ilan Bruchim
Published 2018-06-01

Oncogenic fusion proteins adopt the insulin-like growth factor signaling pathway

by Haim Werner, Shilhav Meisel-Sharon, Ilan Bruchim
Published 2018-02-01

The mechanism of action of the histone deacetylase inhibitor vorinostat involves interaction with the insulin-like growth factor signaling pathway.

by Rive Sarfstein, Ilan Bruchim, Ami Fishman, Haim Werner
Published 2011-01-01

Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent...

by Rive Sarfstein, Yael Friedman, Zohar Attias-Geva, Ami Fishman, Ilan Bruchim, Haim Werner
Published 2013-01-01

ZYG11A Is Expressed in Epithelial Ovarian Cancer and Correlates With Low Grade Disease

by Laris Achlaug, Lina Somri-Gannam, Lina Somri-Gannam, Shilhav Meisel-Sharon, Shilhav Meisel-Sharon, Rive Sarfstein, Manisha Dixit, Shoshana Yakar, Mordechai Hallak, Mordechai Hallak, Zvi Laron, Haim Werner, Ilan Bruchim, Ilan Bruchim
Published 2021-06-01

Genome-Wide Analyses Identify Filamin-A As a Novel Downstream Target for Insulin and IGF1 Action

by Daniel Aizen, Metsada Pasmanik-Chor, Rive Sarfstein, Zvi Laron, Ilan Bruchim, Haim Werner, Haim Werner
Published 2018-03-01

IGF1R Axis Inhibition Restores Dendritic Cell Antitumor Response in Ovarian Cancer

by Lina Somri-Gannam, Shilhav Meisel-Sharon, Shay Hantisteanu, Gabriel Groisman, Ofer Limonad, Mordechai Hallak, Ilan Bruchim
Published 2020-08-01