Rate-of-Kill (RoK) assays to triage large compound sets for Chagas disease drug discovery: Application to GSK Chagas Box.

by Juan Cantizani, Pablo Gamallo, Ignacio Cotillo, Raquel Alvarez-Velilla, Julio Martin
Published 2021-07-01

Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas' disease drug discovery.

by Lorna M MacLean, John Thomas, Michael D Lewis, Ignacio Cotillo, David W Gray, Manu De Rycker
Published 2018-07-01

Novel chemical starting points for drug discovery in leishmaniasis and Chagas disease

by Irene Roquero, Juan Cantizani, Ignacio Cotillo, M. Pilar Manzano, Albane Kessler, J. Julio Martín, Case W. McNamara
Published 2019-08-01

Automated high-content assay for compounds selectively toxic to Trypanosoma cruzi in a myoblastic cell line.

by Julio Alonso-Padilla, Ignacio Cotillo, Jesús L Presa, Juan Cantizani, Imanol Peña, Ana I Bardera, Jose J Martín, Ana Rodriguez
Published 2015-01-01

Phenyldihydropyrazolones as Novel Lead Compounds Against Trypanosoma cruzi

by Maarten Sijm, Julianna Siciliano de Araújo, Stefan Kunz, Susanne Schroeder, Ewald Edink, Kristina M. Orrling, An Matheeussen, Tiffany van de Meer, Payman Sadek, Hans Custers, Ignacio Cotillo, Julio J. Martin, Marco Siderius, Louis Maes, David G. Brown, Maria de Nazaré Correia Soeiro, GeertJan Sterk, Iwan J.P. de Esch, Rob Leurs
Published 2019-04-01