Molecular target: pan-AKT in gastric cancer

by Ian Chau, Byung Woog Kang
Published 2020-10-01

Ramucirumab for advanced gastric cancer or gastro-oesophageal junction adenocarcinoma

by Kate Young, Elizabeth Smyth, Ian Chau
Published 2015-11-01

Targeting the Stroma in the Management of Pancreatic Cancer

by Penelope Edwards, Byung Woog Kang, Ian Chau
Published 2021-07-01

Targeting Vascular Endothelial Growth Factor in Oesophagogastric Cancer: A Review of Progress to Date and Immunotherapy Combination Strategies

by Oliver Butters, Kate Young, David Cunningham, Ian Chau, Naureen Starling
Published 2019-07-01

Efficacy and toxicity of salvage weekly paclitaxel chemotherapy in non-Asian patients with advanced oesophagogastric adenocarcinoma

by Noelia Tarazona, Elizabeth C. Smyth, Clare Peckit, Ian Chau, David Watkins, Sheela Rao, Naureen Starling, David Cunningham
Published 2016-03-01

Real-world treatment patterns, healthcare resource use and clinical outcomes of patients receiving second line therapy for advanced or metastatic gastric cancer

by David Gómez-Ulloa, Mayur Amonkar, Smita Kothari, Winson Y. Cheung, Ian Chau, John R. Zalcberg, Núria Lara Suriñach, Alfredo Falcone
Published 2020-05-01

Safety and Effectiveness of Aflibercept + Fluorouracil, Leucovorin, and Irinotecan (FOLFIRI) for the Treatment of Patients with Metastatic Colorectal Cancer (mCRC) in Current Clini...

by Ian Chau, Marwan Fakih, Pilar García-Alfonso, Zdenĕk Linke, Ana Ruiz Casado, Eduardo Polo Marques, Pascaline Picard, Marina Celanovic, Thomas Cartwright
Published 2020-03-01

Outcomes of Patients with Early Onset Colorectal Cancer Treated in a UK Specialist Cancer Center

by Alexandros Georgiou, Shelize Khakoo, Penelope Edwards, Anna Minchom, Kyriakos Kouvelakis, Eleftheria Kalaitzaki, Natalie Nobar, Vanessa Calamai, Maria Ifijen, Olga Husson, David Watkins, Sheela Rao, Ian Chau, David Cunningham, Naureen Starling
Published 2019-10-01

Detecting and Tracking Circulating Tumour DNA Copy Number Profiles during First Line Chemotherapy in Oesophagogastric Adenocarcinoma

by Michael Davidson, Louise J. Barber, Andrew Woolston, Catherine Cafferkey, Sonia Mansukhani, Beatrice Griffiths, Sing-Yu Moorcraft, Isma Rana, Ruwaida Begum, Ioannis Assiotis, Nik Matthews, Sheela Rao, David Watkins, Ian Chau, David Cunningham, Naureen Starling, Marco Gerlinger
Published 2019-05-01

Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis (the EASI-SWITCH trial): study protocol for a randomised contr...

by Caroline Forde, Ronan McMullan, Mike Clarke, Richard H. Wilson, Ruth Plummer, Margaret Grayson, Cliona McDowell, Ashley Agus, Annmarie Doran, Danny F. McAuley, Anne L. Thomas, Rosemary A. Barnes, Richard Adams, Ian Chau, Vicky Coyle
Published 2020-05-01

Ramucirumab in Combination with Pembrolizumab in Treatment-Naïve Advanced Gastric or GEJ Adenocarcinoma: Safety and Antitumor Activity from the Phase 1a/b JVDF Trial

by Ian Chau, Nicolas Penel, Andres O. Soriano, Hendrik-Tobias Arkenau, Jennifer Cultrera, Rafael Santana-Davila, Emiliano Calvo, Christophe Le Tourneau, Lars Zender, Johanna C. Bendell, Gu Mi, Ling Gao, Samuel Clark McNeely, Joana M. Oliveira, David Ferry, Roy S. Herbst, Charles S. Fuchs
Published 2020-10-01

The Mutational Concordance of Fixed Formalin Paraffin Embedded and Fresh Frozen Gastro-Oesophageal Tumours Using Whole Exome Sequencing

by Irene Y. Chong, Naureen Starling, Alistair Rust, John Alexander, Lauren Aronson, Marta Llorca-Cardenosa, Ritika Chauhan, Asif Chaudry, Sacheen Kumar, Kerry Fenwick, Ioannis Assiotis, Nik Matthews, Ruwaida Begum, Andrew Wotherspoon, Monica Terlizzo, David Watkins, Ian Chau, Christopher J. Lord, Syed Haider, Sheela Rao, David Cunningham
Published 2021-01-01

Immunopeptidomics of colorectal cancer organoids reveals a sparse HLA class I neoantigen landscape and no increase in neoantigens with interferon or MEK-inhibitor treatment

by Alice Newey, Beatrice Griffiths, Justine Michaux, Hui Song Pak, Brian J. Stevenson, Andrew Woolston, Maria Semiannikova, Georgia Spain, Louise J. Barber, Nik Matthews, Sheela Rao, David Watkins, Ian Chau, George Coukos, Julien Racle, David Gfeller, Naureen Starling, David Cunningham, Michal Bassani-Sternberg, Marco Gerlinger
Published 2019-11-01

KRAS and BRAF mutations in circulating tumour DNA from locally advanced rectal cancer

by Francesco Sclafani, Ian Chau, David Cunningham, Jens C. Hahne, George Vlachogiannis, Zakaria Eltahir, Andrea Lampis, Chiara Braconi, Eleftheria Kalaitzaki, David Gonzalez De Castro, Andrew Wotherspoon, Jaume Capdevila, Bengt Glimelius, Noelia Tarazona, Ruwaida Begum, Hazel Lote, Sanna Hulkki Wilson, Giulia Mentrasti, Gina Brown, Diana Tait, Jacqueline Oates, Nicola Valeri
Published 2018-01-01

Diagnostic Accuracy and Safety of Coaxial System in Oncology Patients Treated in a Specialist Cancer Center With Prospective Validation Within Clinical Trial Data

by Khurum Khan, Reyes Gonzalez-Exposito, David Cunningham, Dow-Mu Koh, Andrew Woolston, Louise Barber, Beatrice Griffiths, Kyriakos Kouvelakis, Vanessa Calamai, Monia Bali, Nasir Khan, Annette Bryant, Claire Saffery, Charles Dearman, Ruwaida Begum, Sheela Rao, Naureen Starling, David Watkins, Ian Chau, Chiara Braconi, Nicola Valeri, Nicola Valeri, Marco Gerlinger, Marco Gerlinger, Nicos Fotiadis
Published 2020-09-01

CEA expression heterogeneity and plasticity confer resistance to the CEA-targeting bispecific immunotherapy antibody cibisatamab (CEA-TCB) in patient-derived colorectal cancer orga...

by Reyes Gonzalez-Exposito, Maria Semiannikova, Beatrice Griffiths, Khurum Khan, Louise J. Barber, Andrew Woolston, Georgia Spain, Katharina von Loga, Ben Challoner, Radhika Patel, Michael Ranes, Amanda Swain, Janet Thomas, Annette Bryant, Claire Saffery, Nicos Fotiadis, Sebastian Guettler, David Mansfield, Alan Melcher, Thomas Powles, Sheela Rao, David Watkins, Ian Chau, Nik Matthews, Fredrik Wallberg, Naureen Starling, David Cunningham, Marco Gerlinger
Published 2019-04-01