The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in <i>KRAS</i>-Driven Lung Cancer

by Seon-Hyeong Lee, Yoon Jeon, Joon Hee Kang, Hyonchol Jang, Ho Lee, Soo-Youl Kim
Published 2020-05-01

Crystal Structure of the Kinase Domain of MerTK in Complex with AZD7762 Provides Clues for Structure-Based Drug Development

by Tae Hyun Park, Seung-Hyun Bae, Seoung Min Bong, Seong Eon Ryu, Hyonchol Jang, Byung Il Lee
Published 2020-10-01

Reply to Krupenko et al. Comment on “Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer <em>Cancers</...

by Seon-Hyeong Lee, Yoon Jeon, Joon-Hee Kang, Hyonchol Jang, Kyeong-Man Hong, Dongwan Hong, Ho Lee, Soo-Youl Kim
Published 2021-05-01

FAM188B Downregulation Sensitizes Lung Cancer Cells to Anoikis via EGFR Downregulation and Inhibits Tumor Metastasis In Vivo

by Eun-Ju Jang, Jee Young Sung, Ha-Eun Yoo, Hyonchol Jang, Jaegal Shim, Eok-Soo Oh, Sung-Ho Goh, Yong-Nyun Kim
Published 2021-01-01

Oxoglutarate Carrier Inhibition Reduced Melanoma Growth and Invasion by Reducing ATP Production

by Jae-Seon Lee, Jiwon Choi, Seon-Hyeong Lee, Joon Hee Kang, Ji Sun Ha, Hee Yeon Kim, Hyonchol Jang, Jong In Yook, Soo-Youl Kim
Published 2020-11-01

False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases.

by Young-Ho Kim, Yura Song, Jong-Kwang Kim, Tae-Min Kim, Hye Won Sim, Hyung-Lae Kim, Hyonchol Jang, Young-Woo Kim, Kyeong-Man Hong
Published 2019-01-01

Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres

by Hee Yeon Kim, Byung Il Lee, Ji Hoon Jeon, Dong Keon Kim, Seok-Gu Kang, Jin-Kyoung Shim, Soo Youl Kim, Sang Won Kang, Hyonchol Jang
Published 2019-10-01

Targeting Oxidative Phosphorylation Reverses Drug Resistance in Cancer Cells by Blocking Autophagy Recycling

by Jae-Seon Lee, Ho Lee, Hyonchol Jang, Sang Myung Woo, Jong Bae Park, Seon-Hyeong Lee, Joon Hee Kang, Hee Yeon Kim, Jaewhan Song, Soo-Youl Kim
Published 2020-09-01

ATP Production Relies on Fatty Acid Oxidation Rather than Glycolysis in Pancreatic Ductal Adenocarcinoma

by Jae-Seon Lee, Su-Jin Oh, Hyun-Jung Choi, Joon Hee Kang, Seon-Hyeong Lee, Ji Sun Ha, Sang Myung Woo, Hyonchol Jang, Ho Lee, Soo-Youl Kim
Published 2020-09-01

<i>FAK</i>-Copy-Gain Is a Predictive Marker for Sensitivity to FAK Inhibition in Breast Cancer

by Young-Ho Kim, Hyun-Kyoung Kim, Hee Yeon Kim, HyeRan Gawk, Seung-Hyun Bae, Hye Won Sim, Eun-Kyung Kang, Ju-Young Seoh, Hyonchol Jang, Kyeong-Man Hong
Published 2019-09-01

Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells

by Jihoon Shin, Tae Wan Kim, Hyunsoo Kim, Hye Ji Kim, Min Young Suh, Sangho Lee, Han-Teo Lee, Sojung Kwak, Sang-Eun Lee, Jong-Hyuk Lee, Hyonchol Jang, Eun-Jung Cho, Hong-Duk Youn
Published 2016-02-01

PGC1α Loss Promotes Lung Cancer Metastasis through Epithelial-Mesenchymal Transition

by Taek-In Oh, Mingyu Lee, Yoon-Mi Lee, Geon-Hee Kim, Daekee Lee, Jueng Soo You, Sun Ha Kim, Minyoung Choi, Hyonchol Jang, Yeong-Min Park, Hyun-Woo Shin, Dong Hoon Shin, Ji-Hong Lim
Published 2021-04-01

Cancer cells undergoing epigenetic transition show short-term resistance and are transformed into cells with medium-term resistance by drug treatment

by Shiv Poojan, Seung-Hyun Bae, Jae-Woong Min, Eun Young Lee, Yura Song, Hee Yeon Kim, Hye Won Sim, Eun-Kyung Kang, Young-Ho Kim, Hae-Ock Lee, Yourae Hong, Woong-Yang Park, Hyonchol Jang, Kyeong-Man Hong
Published 2020-07-01

Phosphorylation of OCT4 Serine 236 Inhibits Germ Cell Tumor Growth by Inducing Differentiation

by Dong-Keon Kim, Bomin Song, Suji Han, Hansol Jang, Seung-Hyun Bae, Hee Yeon Kim, Seon-Hyeong Lee, Seungjin Lee, Jong Kwang Kim, Han-Seong Kim, Kyeong-Man Hong, Byung Il Lee, Hong-Duk Youn, Soo-Youl Kim, Sang Won Kang, Hyonchol Jang
Published 2020-09-01

Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness

by Hee Yeon Kim, Dong Keon Kim, Seung-Hyun Bae, HyeRan Gwak, Ji Hoon Jeon, Jong Kwang Kim, Byung Il Lee, Hye Jin You, Dong Hoon Shin, Young-Ho Kim, Soo Youl Kim, Sung-Sik Han, Jin-Kyoung Shim, Ji-Hyun Lee, Seok-Gu Kang, Hyonchol Jang
Published 2018-10-01