Biosynthesis and mechanism of action of antitumor antibiotics

by Hurley, Laurence H.
Published 1996

A Mechanosensor Mechanism Controls the G-Quadruplex/i-Motif Molecular Switch in the MYC Promoter NHE III 1

by Sutherland, Caleb, Cui, Yunxi, Mao, Hanbin, Hurley, Laurence H.
Published 2016

Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA

by Weldon, Carika, Behm-Ansmant, Isabelle, Hurley, Laurence H, Burley, Glenn A, Branlant, Christiane, Eperon, Ian C, Dominguez, Cyril
Published 2016

Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X

by Weldon, Carika, Dacanay, Justine G, Gokhale, Vijay, Boddupally, Peda Venkat L, Behm-Ansmant, Isabelle, Burley, Glenn A, Branlant, Christiane, Hurley, Laurence H, Dominguez, Cyril, Eperon, Ian C
Published 2018

The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer

by Hahn, Tobias, Bradley-Dunlop, Deborah, Hurley, Laurence, Von-Hoff, Daniel, Gately, Stephen, Mary, Disis, Lu, Hailing, Penichet, Manuel, Besselsen, David, Cole, Brook, Meeuwsen, Tanisha, Walker, Edwin, Akporiaye, Emmanuel
Published 2011

A Pharmacological Chaperone Molecule Induces Cancer Cell Death by Restoring Tertiary DNA Structures in Mutant hTERT Promoters

by Kang, Hyun-Jin, Cui, Yunxi, Yin, Holly, Scheid, Amy, Hendricks, William P. D., Schmidt, Jessica, Sekulic, Aleksandar, Kong, Deming, Trent, Jeffrey M., Gokhale, Vijay, Mao, Hanbin, Hurley, Laurence H.
Published 2016

The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer

by Penichet Manuel L, Lu Hailing, Mary Disis L, Gately Stephen, Von-Hoff Daniel, Hurley Laurence H, Bradley-Dunlop Deborah J, Hahn Tobias, Besselsen David G, Cole Brook B, Meeuwsen Tanisha, Walker Edwin, Akporiaye Emmanuel T
Published 2011-11-01

MYC Inhibition Through Small Compound Targeting of the NHE III₁ i-Motif

by Neeb, Megan Ann
Published 2015

The Regulatory Significance and Molecular Targeting of Novel Non-B-DNA Secondary Structures Formed from the PDGFR-Beta Core Promoter Nuclease Hypersensitivity Element

by Brown, Robert Vincent
Published 2014

Characterization of Secondary DNA Structures Formed in the c-myb and hTERT Promoters and Their Potential Role in the Regulation of Transcription

by Palumbo, SunMi Lee
Published 2009

Targeting the Promoter Regions of PDGF Ligand and Receptor

by Qin, Yong
Published 2008

Design, Synthesis and Biological Evaluation of c-MYC G-Quadruplex Interactive Agents

by Sharma, Chandana
Published 2006

Targeting the Aurora Kinases to Treat Pancreatic Cancer

by Warner, Steven Lawrence
Published 2005

Characterization and Molecular Targeting of a Mechanosensor Mechanism Controlled By the G-Quadruplex/I-Motif Molecular Switch in the MYC Promoter NHE III₁

by Sutherland, Caleb Daniel
Published 2015

CHARACTERIZATION AND TARGETING OF THE MULTIPLE DNA SECONDARY STRUCTURES IN THE KRAS PROXIMAL PROMOTER TO MODULATE GENE EXPRESSION

by Kaiser, Christine Elizabeth
Published 2015

Defining the Role of Nucleolin on the Transcriptional Regulation of c-MYC through Modulation of the c-MYC NHE III1 Element.

by Gonzalez, Veronica
Published 2010

Defining the Role of DNA Secondary Structures and Transcriptional Factors in the Control of c-myc and bcl-2 Expression

by Dexheimer, Thomas Steven
Published 2006

Identification and Development of Novel Compounds for the Treatment of Human Cancers

by Carey, Steven Spencer
Published 2008

The Design, Synthesis, and Evaluation of Novel DFG-out Allosteric Kinase Inhibitors

by Dietrich, Justin David
Published 2008

Characterization and Molecular Targeting of the Bcl-2 i-Motif for Modulation of Gene Expression and Induction of Chemosensitivity in Lymphoma

by Kendrick, Samantha Lynn
Published 2010