AMPK maintains TCA cycle through sequential phosphorylation of PDHA to promote tumor metastasis

by Zhen Cai, Danni Peng, Hui-Kuan Lin
Published 2020-11-01

Systematically understanding the immunity leading to CRPC progression.

by Zhiwei Ji, Weiling Zhao, Hui-Kuan Lin, Xiaobo Zhou
Published 2019-09-01

Regulation of Skp2 Expression and Activity and Its Role in Cancer Progression

by Chia-Hsin Chan, Szu-Wei Lee, Jing Wang, Hui-Kuan Lin
Published 2010-01-01

Phosphorylation by mTORC1 stablizes Skp2 and regulates its oncogenic function in gastric cancer

by Qirong Geng, Jianjun Liu, Zhaohui Gong, Shangxiang Chen, Shuai Chen, Xiaoxing Li, Yue Lu, Xiaofeng Zhu, Hui-kuan Lin, Dazhi Xu
Published 2017-04-01

Novel inhibitors induce large conformational changes of GAB1 pleckstrin homology domain and kill breast cancer cells.

by Lu Chen, Lei Du-Cuny, Sylvestor Moses, Sabrina Dumas, Zuohe Song, Abdol Hossein Rezaeian, Hui-Kuan Lin, Emmanuelle J Meuillet, Shuxing Zhang
Published 2015-01-01

The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance

by Fei Han, Chien-Feng Li, Zhen Cai, Xian Zhang, Guoxiang Jin, Wei-Na Zhang, Chuan Xu, Chi-Yun Wang, John Morrow, Shuxing Zhang, Dazhi Xu, Guihua Wang, Hui-Kuan Lin
Published 2018-11-01

Ubiquitin Carboxyl-Terminal Hydrolase L1 (UCHL1) Promotes Uterine Serous Cancer Cell Proliferation and Cell Cycle Progression

by Suet-Ying Kwan, Chi-Lam Au-Yeung, Tsz-Lun Yeung, Angela Rynne-Vidal, Kwong-Kwok Wong, John I. Risinger, Hui-Kuan Lin, Rosemarie E. Schmandt, Melinda S. Yates, Samuel C. Mok, Karen H. Lu
Published 2020-01-01

H3 ubiquitination by NEDD4 regulates H3 acetylation and tumorigenesis

by Xian Zhang, Binkui Li, Abdol Hossein Rezaeian, Xiaohong Xu, Ping-Chieh Chou, Guoxiang Jin, Fei Han, Bo-Syong Pan, Chi-Yun Wang, Jie Long, Anmei Zhang, Chih-Yang Huang, Fuu-Jen Tsai, Chang-Hai Tsai, Christopher Logothetis, Hui-Kuan Lin
Published 2017-03-01

Identification of Plasma Glycosphingolipids as Potential Biomarkers for Prostate Cancer (PCa) Status

by Ashley J. Snider, Michael C. Seeds, Laurel Johnstone, Justin M. Snider, Brian Hallmark, Rahul Dutta, Cristina Moraga Franco, John S. Parks, Jeannette T. Bensen, Corey D. Broeckling, James L. Mohler, Gary J. Smith, Elizabeth T.H. Fontham, Hui-Kuan Lin, William Bresette, Susan Sergeant, Floyd H. Chilton
Published 2020-09-01

Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice.

by Betty Lamothe, Yunju Lai, Lana Hur, Natalia Martin Orozco, Jing Wang, Alejandro D Campos, Min Xie, Michael D Schneider, Cynthia R Lockworth, Jared Jakacky, Diep Tran, Michael Ho, Sity Dawud, Chen Dong, Hui-Kuan Lin, Peter Hu, Zeev Estrov, Carlos E Bueso-Ramos, Bryant G Darnay
Published 2012-01-01

Mir20a/106a-WTX axis regulates RhoGDIa/CDC42 signaling and colon cancer progression

by Gui-fang Zhu, Yang-wei Xu, Jian Li, Hui-lin Niu, Wen-xia Ma, Jia Xu, Pei-rong Zhou, Xia Liu, Dan-li Ye, Xiao-rong Liu, Tao Yan, Wei-ke Zhai, Zhi-jun Xu, Chun Liu, Lei Wang, Hao Wang, Jia-mao Luo, Li Liu, Xuan-qi Li, Suiqun Guo, Hui-ping Jiang, Peng Shen, Hui-kuan Lin, Di-hua Yu, Yan-qing Ding, Qing-ling Zhang
Published 2019-01-01

Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium chann...

by Hugo Jimenez, Minghui Wang, Jacquelyn W. Zimmerman, Michael J. Pennison, Sambad Sharma, Trevor Surratt, Zhi-Xiang Xu, Ivan Brezovich, Devin Absher, Richard M. Myers, Barry DeYoung, David L. Caudell, Dongquan Chen, Hui-Wen Lo, Hui-Kuan Lin, Dwayne W. Godwin, Michael Olivier, Anand Ghanekar, Kui Chen, Lance D. Miller, Yijian Gong, Myles Capstick, Ralph B. D'Agostino, Jr, Reginald Munden, Philippe Merle, Alexandre Barbault, Arthur W. Blackstock, Herbert L. Bonkovsky, Guang-Yu Yang, Guangxu Jin, Liang Liu, Wei Zhang, Kounosuke Watabe, Carl F. Blackman, Boris C. Pasche
Published 2019-06-01