Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation.

by Chih-Hsin Lai, Ying-Jung J Lai, Feng-Pai Chou, Hsiang-Hua D Chang, Chun-Che Tseng, Michael D Johnson, Jehng-Kang Wang, Chen-Yong Lin
Published 2016-01-01

Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells.

by Hsiang-Hua D Chang, Yuan Xu, Hongyu Lai, Xiaoyu Yang, Chun-Che Tseng, Ying-Jung J Lai, Yu Pan, Emily Zhou, Michael D Johnson, Jehng-Kang Wang, Chen-Yong Lin
Published 2015-01-01

N-Glycan Branching Affects the Subcellular Distribution of and Inhibition of Matriptase by HAI-2/Placental Bikunin.

by Ying-Jung J Lai, Hsiang-Hua D Chang, Hongyu Lai, Yuan Xu, Frank Shiao, Nanxi Huang, Linpei Li, Ming-Shyue Lee, Ming-Shyue Lee, Michael D Johnson, Jehng-Kang Wang, Chen-Yong Lin
Published 2015-01-01

Matriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane

by Chih-Hsin Lai, Shun-Cheng Chang, Yen-Ju Chen, Yi-Jie J. Wang, Ying-Jun J. Lai, Hsiang-Hua D. Chang, Eric B. Berens, Michael D. Johnson, Jehng-Kang Wang, Chen-Yong Lin
Published 2016-10-01

Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner.

by Hui Chen Su, Yan A Liang, Ying-Jung J Lai, Yi-Lin Chiu, Robert B Barndt, Frank Shiao, Hsiang-Hua D Chang, Dajun D Lu, Nanxi Huang, Chun-Che Tseng, Jehng-Kang Wang, Ming-Shyue Lee, Michael D Johnson, Shih-Ming Huang, Chen-Yong Lin
Published 2016-01-01