Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism

by Jiani Wang, Michelle Cheng, Ivy K.M. Law, Christina Ortiz, Mingjun Sun, Hon Wai Koon
Published 2019-03-01

High circulating elafin levels are associated with Crohn's disease-associated intestinal strictures.

by Jiani Wang, Christina Ortiz, Lindsey Fontenot, Ying Xie, Wendy Ho, S Anjani Mattai, David Q Shih, Hon Wai Koon
Published 2020-01-01

Substance P Mediates Proinflammatory Cytokine Release From Mesenteric Adipocytes in Inflammatory Bowel Disease PatientsSummary

by Aristea Sideri, Kyriaki Bakirtzi, David Q. Shih, Hon Wai Koon, Phillip Fleshner, Razvan Arsenescu, Violeta Arsenescu, Jerrold R. Turner, Iordanes Karagiannides, Charalabos Pothoulakis
Published 2015-07-01

Transgenic mice over-expressing ET-1 in the endothelial cells develop systemic hypertension with altered vascular reactivity.

by Justin Wai-Chung Leung, Wing Tak Wong, Hon Wai Koon, Fong Ming Mo, Sidney Tam, Yu Huang, Paul M Vanhoutte, Stephen Sum Man Chung, Sookja Kim Chung
Published 2011-01-01

Constitutive TL1A (TNFSF15) expression on lymphoid or myeloid cells leads to mild intestinal inflammation and fibrosis.

by David Q Shih, Robert Barrett, Xiaolan Zhang, Nicole Yeager, Hon Wai Koon, Piangwarin Phaosawasdi, Yahui Song, Brian Ko, Michelle H Wong, Kathrin S Michelsen, Gislaine Martins, Charalabos Pothoulakis, Stephan R Targan
Published 2011-01-01

Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammato...

by Diana Hoang-Ngoc Tran, Jiani Wang, Christina Ha, Wendy Ho, S. Anjani Mattai, Angelos Oikonomopoulos, Guy Weiss, Precious Lacey, Michelle Cheng, Christine Shieh, Caroline C. Mussatto, Samantha Ho, Daniel Hommes, Hon Wai Koon
Published 2017-05-01

Antifibrogenic Effects of the Antimicrobial Peptide Cathelicidin in Murine Colitis-Associated FibrosisSummary

by Jun Hwan Yoo, Samantha Ho, Deanna Hoang-Yen Tran, Michelle Cheng, Kyriaki Bakirtzi, Yuzu Kubota, Ryan Ichikawa, Bowei Su, Diana Hoang-Ngoc Tran, Tressia C. Hing, Irene Chang, David Q. Shih, Richard E. Issacson, Richard L. Gallo, Claudio Fiocchi, Charalabos Pothoulakis, Hon Wai Koon
Published 2015-01-01