Transmission of a 2009 H1N1 pandemic influenza virus occurs before fever is detected, in the ferret model.

by Kim L Roberts, Holly Shelton, Peter Stilwell, Wendy S Barclay
Published 2012-01-01

Low pathogenic avian influenza virus infection retards colon microbiota diversification in two different chicken lines

by Klaudia Chrzastek, Joy Leng, Mohammad Khalid Zakaria, Dagmara Bialy, Roberto La Ragione, Holly Shelton
Published 2021-09-01

Mutations in H5N1 influenza virus hemagglutinin that confer binding to human tracheal airway epithelium.

by Guadalupe Ayora-Talavera, Holly Shelton, Margaret A Scull, Junyuan Ren, Ian M Jones, Raymond J Pickles, Wendy S Barclay
Published 2009-11-01

A single amino acid in the HA of pH1N1 2009 influenza virus affects cell tropism in human airway epithelium, but not transmission in ferrets.

by Neeltje van Doremalen, Holly Shelton, Kim L Roberts, Ian M Jones, Ray J Pickles, Catherine I Thompson, Wendy S Barclay
Published 2011-01-01

Internal genes of a highly pathogenic H5N1 influenza virus determine high viral replication in myeloid cells and severe outcome of infection in mice.

by Hui Li, Konrad C Bradley, Jason S Long, Rebecca Frise, Jonathan W Ashcroft, Lorian C Hartgroves, Holly Shelton, Spyridon Makris, Cecilia Johansson, Bin Cao, Wendy S Barclay
Published 2018-01-01

Species specific differences in use of ANP32 proteins by influenza A virus

by Jason S Long, Alewo Idoko-Akoh, Bhakti Mistry, Daniel Goldhill, Ecco Staller, Jocelyn Schreyer, Craig Ross, Steve Goodbourn, Holly Shelton, Michael A Skinner, Helen Sang, Michael J McGrew, Wendy Barclay
Published 2019-06-01

Association of Increased Receptor-Binding Avidity of Influenza A(H9N2) Viruses with Escape from Antibody-Based Immunity and Enhanced Zoonotic Potential

by Joshua E. Sealy, Tahir Yaqub, Thomas P. Peacock, Pengxiang Chang, Burcu Ermetal, Anabel Clements, Jean-Remy Sadeyen, Arslan Mehboob, Holly Shelton, Juliet E. Bryant, Rod S. Daniels, John W. McCauley, Munir Iqbal
Published 2019-01-01

The SARS-CoV-2 Spike protein has a broad tropism for mammalian ACE2 proteins.

by Carina Conceicao, Nazia Thakur, Stacey Human, James T Kelly, Leanne Logan, Dagmara Bialy, Sushant Bhat, Phoebe Stevenson-Leggett, Adrian K Zagrajek, Philippa Hollinghurst, Michal Varga, Christina Tsirigoti, Matthew Tully, Chris Chiu, Katy Moffat, Adrian Paul Silesian, John A Hammond, Helena J Maier, Erica Bickerton, Holly Shelton, Isabelle Dietrich, Stephen C Graham, Dalan Bailey
Published 2020-12-01

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

by Tiong Kit Tan, Pramila Rijal, Rolle Rahikainen, Anthony H. Keeble, Lisa Schimanski, Saira Hussain, Ruth Harvey, Jack W. P. Hayes, Jane C. Edwards, Rebecca K. McLean, Veronica Martini, Miriam Pedrera, Nazia Thakur, Carina Conceicao, Isabelle Dietrich, Holly Shelton, Anna Ludi, Ginette Wilsden, Clare Browning, Adrian K. Zagrajek, Dagmara Bialy, Sushant Bhat, Phoebe Stevenson-Leggett, Philippa Hollinghurst, Matthew Tully, Katy Moffat, Chris Chiu, Ryan Waters, Ashley Gray, Mehreen Azhar, Valerie Mioulet, Joseph Newman, Amin S. Asfor, Alison Burman, Sylvia Crossley, John A. Hammond, Elma Tchilian, Bryan Charleston, Dalan Bailey, Tobias J. Tuthill, Simon P. Graham, Helen M. E. Duyvesteyn, Tomas Malinauskas, Jiandong Huo, Julia A. Tree, Karen R. Buttigieg, Raymond J. Owens, Miles W. Carroll, Rodney S. Daniels, John W. McCauley, David I. Stuart, Kuan-Ying A. Huang, Mark Howarth, Alain R. Townsend
Published 2021-01-01