Mechanisms of regulatory T cell infiltration in tumors: implications for innovative immune precision therapies

by Shohei Koyama, Hiroyoshi Nishikawa
Published 2021-07-01

Transcriptional regulatory network for the establishment of CD8+ T cell exhaustion

by Wooseok Seo, Chandsultana Jerin, Hiroyoshi Nishikawa
Published 2021-02-01

Model-based cell clustering and population tracking for time-series flow cytometry data

by Kodai Minoura, Ko Abe, Yuka Maeda, Hiroyoshi Nishikawa, Teppei Shimamura
Published 2019-12-01

Model-based clustering for flow and mass cytometry data with clinical information

by Ko Abe, Kodai Minoura, Yuka Maeda, Hiroyoshi Nishikawa, Teppei Shimamura
Published 2020-09-01

HSP90 inhibition overcomes EGFR amplification‐induced resistance to third‐generation EGFR‐TKIs

by Sho Watanabe, Yasushi Goto, Hiroyuki Yasuda, Takashi Kohno, Noriko Motoi, Yuichiro Ohe, Hiroyoshi Nishikawa, Susumu S. Kobayashi, Kazuyoshi Kuwano, Yosuke Togashi
Published 2021-03-01

Targeting VEGFR2 with Ramucirumab strongly impacts effector/ activated regulatory T cells and CD8+ T cells in the tumor microenvironment

by Yasuko Tada, Yosuke Togashi, Daisuke Kotani, Takeshi Kuwata, Eichi Sato, Akihito Kawazoe, Toshihiko Doi, Hisashi Wada, Hiroyoshi Nishikawa, Kohei Shitara
Published 2018-10-01

Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes.

by Fumitaka Haseda, Akihisa Imagawa, Hiroyoshi Nishikawa, Shinobu Mitsui, Chiharu Tsutsumi, Reiko Fujisawa, Hiroyuki Sano, Yuko Murase-Mishiba, Jungo Terasaki, Shimon Sakaguchi, Toshiaki Hanafusa
Published 2016-01-01

Importance of lymph node immune responses in MSI-H/dMMR colorectal cancer

by Koji Inamori, Yosuke Togashi, Shota Fukuoka, Kiwamu Akagi, Kouetsu Ogasawara, Takuma Irie, Daisuke Motooka, Yoichi Kobayashi, Daisuke Sugiyama, Motohiro Kojima, Norihiko Shiiya, Shota Nakamura, Shoichi Maruyama, Yutaka Suzuki, Masaaki Ito, Hiroyoshi Nishikawa
Published 2021-05-01

TENERGY: multicenter phase II study of Atezolizumab monotherapy following definitive Chemoradiotherapy with 5-FU plus Cisplatin in patients with unresectable locally advanced esoph...

by Hideaki Bando, Daisuke Kotani, Takahiro Tsushima, Hiroki Hara, Shigenori Kadowaki, Ken Kato, Keisho Chin, Kensei Yamaguchi, Shun-ichiro Kageyama, Hidehiro Hojo, Masaki Nakamura, Hidenobu Tachibana, Masashi Wakabayashi, Miki Fukutani, Yosuke Togashi, Nozomu Fuse, Hiroyoshi Nishikawa, Takashi Kojima
Published 2020-04-01

Potentiality of multiple modalities for single-cell analyses to evaluate the tumor microenvironment in clinical specimens

by Yukie Kashima, Yosuke Togashi, Shota Fukuoka, Takahiro Kamada, Takuma Irie, Ayako Suzuki, Yoshiaki Nakamura, Kohei Shitara, Tatsunori Minamide, Taku Yoshida, Naofumi Taoka, Tatsuya Kawase, Teiji Wada, Koichiro Inaki, Masataka Chihara, Yukihiko Ebisuno, Sakiyo Tsukamoto, Ryo Fujii, Akihiro Ohashi, Yutaka Suzuki, Katsuya Tsuchihara, Hiroyoshi Nishikawa, Toshihiko Doi
Published 2021-01-01

Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

by Tiina Kelkka, Tiina Kelkka, Tiina Kelkka, Tiina Kelkka, Paula Savola, Paula Savola, Paula Savola, Paula Savola, Dipabarna Bhattacharya, Dipabarna Bhattacharya, Dipabarna Bhattacharya, Dipabarna Bhattacharya, Jani Huuhtanen, Jani Huuhtanen, Jani Huuhtanen, Jani Huuhtanen, Tapio Lönnberg, Matti Kankainen, Matti Kankainen, Matti Kankainen, Kirsi Paalanen, Mikko Tyster, Mikko Tyster, Mikko Tyster, Mikko Tyster, Maija Lepistö, Pekka Ellonen, Johannes Smolander, Samuli Eldfors, Bhagwan Yadav, Bhagwan Yadav, Bhagwan Yadav, Bhagwan Yadav, Sofia Khan, Riitta Koivuniemi, Christopher Sjöwall, Laura L. Elo, Laura L. Elo, Harri Lähdesmäki, Yuka Maeda, Hiroyoshi Nishikawa, Marjatta Leirisalo-Repo, Tuulikki Sokka-Isler, Tuulikki Sokka-Isler, Satu Mustjoki, Satu Mustjoki, Satu Mustjoki, Satu Mustjoki
Published 2020-11-01

Corrigendum: Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature

by Tiina Kelkka, Tiina Kelkka, Tiina Kelkka, Tiina Kelkka, Paula Savola, Paula Savola, Paula Savola, Paula Savola, Dipabarna Bhattacharya, Dipabarna Bhattacharya, Dipabarna Bhattacharya, Dipabarna Bhattacharya, Jani Huuhtanen, Jani Huuhtanen, Jani Huuhtanen, Jani Huuhtanen, Tapio Lönnberg, Matti Kankainen, Matti Kankainen, Matti Kankainen, Kirsi Paalanen, Mikko Tyster, Mikko Tyster, Mikko Tyster, Mikko Tyster, Maija Lepistö, Pekka Ellonen, Johannes Smolander, Samuli Eldfors, Bhagwan Yadav, Bhagwan Yadav, Bhagwan Yadav, Bhagwan Yadav, Sofia Khan, Riitta Koivuniemi, Christopher Sjöwall, Laura L. Elo, Laura L. Elo, Harri Lähdesmäki, Yuka Maeda, Hiroyoshi Nishikawa, Marjatta Leirisalo-Repo, Tuulikki Sokka-Isler, Tuulikki Sokka-Isler, Satu Mustjoki, Satu Mustjoki, Satu Mustjoki, Satu Mustjoki
Published 2021-05-01