Delta Opioid Receptor Agonists Ameliorate Colonic Inflammation by Modulating Immune Responses

by Kazuki Nagata, Hiroshi Nagase, Ayumi Okuzumi, Chiharu Nishiyama
Published 2021-09-01

Development and use of a digital signage system for revitalizing regional shopping districts

by Shota Takata, Kengo Hayashi, Keita Tamatsu, Yoshio Yamagishi, Hiroshi Nagase
Published 2014-12-01

Potential Anxiolytic and Antidepressant-Like Activities of SNC80, a Selective δ-Opioid Agonist, in Behavioral Models in Rodents

by Akiyoshi Saitoh, Yuji Kimura, Tomohiko Suzuki, Koji Kawai, Hiroshi Nagase, Junzo Kamei
Published 2004-01-01

Generalization of NMDA-Receptor Antagonists to the Discriminative Stimulus Effects of κ-Opioid Receptor Agonists U-50,488H, but Not TRK-820 in Rats

by Tomohisa Mori, Mutsuko Nomura, Kazumi Yoshizawa, Hiroshi Nagase, Toshiko Sawaguchi, Minoru Narita, Tsutomu Suzuki
Published 2006-01-01

Attenuation of the morphine-induced rewarding effect under chronic inflammatory pain-like state in rats: implication of the activation of endogenous k-opioid system

by Arief Nurrochmad, Kishimoto Yayoi, Ozaki Masahiko, Yoshinori Yajima, Minoru Narita, Hiroshi Nagase, Tsutomu Suzuki
Published 2005-01-01

A delta opioid receptor agonist, KNT-127, in the prelimbic medial prefrontal cortex attenuates glial glutamate transporter blocker-induced anxiety-like behavior in mice

by Akiyoshi Saitoh, Akinobu Soda, Shuhei Kayashima, Kazumi Yoshizawa, Jun-Ichiro Oka, Hiroshi Nagase, Mitsuhiko Yamada
Published 2018-11-01

Systemic administration of a delta opioid receptor agonist, KNT-127, facilitates extinction learning of fear memory in rats

by Azusa Sugiyama, Misa Yamada, Hiroki Furuie, Leo Gotoh, Akiyoshi Saitoh, Hiroshi Nagase, Jun-Ichiro Oka, Mitsuhiko Yamada
Published 2019-03-01

Lack of μ-Opioid Receptor-Mediated G-Protein Activation in the Spinal Cord of Mice Lacking Exon 1 or Exons 2 and 3 of the MOR-1 Gene

by Hirokazu Mizoguchi, Hsiang-En Wu, Minoru Narita, Ichiro Sora, F. Scott Hall, George R. Uhl, Horace H. Loh, Hiroshi Nagase, Leon F. Tseng
Published 2003-01-01

Structure-Activity Relationship between Thiol Group-Trapping Ability of Morphinan Compounds with a Michael Acceptor and Anti-<i>Plasmodium falciparum</i> Activities

by Noriki Kutsumura, Yasuaki Koyama, Tsuyoshi Saitoh, Naoshi Yamamoto, Yasuyuki Nagumo, Yoshiyuki Miyata, Rei Hokari, Aki Ishiyama, Masato Iwatsuki, Kazuhiko Otoguro, Satoshi Ōmura, Hiroshi Nagase
Published 2020-03-01

Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation

by Hurramhon Shokirova, Takenori Inomata, Tsuyoshi Saitoh, Jun Zhu, Kenta Fujio, Yuichi Okumura, Ai Yanagawa, Keiichi Fujimoto, Jaemyoung Sung, Atsuko Eguchi, Maria Miura, Ken Nagino, Kunihiko Hirosawa, Mizu Kuwahara, Yasutsugu Akasaki, Hiroshi Nagase, Akira Murakami
Published 2021-04-01

Peripheral opioid antagonist enhances the effect of anti-tumor drug by blocking a cell growth-suppressive pathway in vivo.

by Masami Suzuki, Fumiko Chiwaki, Yumi Sawada, Maho Ashikawa, Kazuhiko Aoyagi, Takeshi Fujita, Kazuyoshi Yanagihara, Masayuki Komatsu, Minoru Narita, Tsutomu Suzuki, Hiroshi Nagase, Ryoji Kushima, Hiromi Sakamoto, Takeo Fukagawa, Hitoshi Katai, Hitoshi Nakagama, Teruhiko Yoshida, Yasuhito Uezono, Hiroki Sasaki
Published 2015-01-01

Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors

by Yibing Wang, Liqin Cao, Chia-Ying Lee, Tomohiko Matsuo, Kejia Wu, Greg Asher, Lijun Tang, Tsuyoshi Saitoh, Jamie Russell, Daniela Klewe-Nebenius, Li Wang, Shingo Soya, Emi Hasegawa, Yoan Chérasse, Jiamin Zhou, Yuwenbin Li, Tao Wang, Xiaowei Zhan, Chika Miyoshi, Yoko Irukayama, Jie Cao, Julian P. Meeks, Laurent Gautron, Zhiqiang Wang, Katsuyasu Sakurai, Hiromasa Funato, Takeshi Sakurai, Masashi Yanagisawa, Hiroshi Nagase, Reiko Kobayakawa, Ko Kobayakawa, Bruce Beutler, Qinghua Liu
Published 2018-05-01