Diabetic condition induces hypertrophy and vacuolization in glomerular parietal epithelial cells

by Takahisa Kawaguchi, Kazuhiro Hasegawa, Itaru Yasuda, Hirokazu Muraoka, Hiroyuki Umino, Hirobumi Tokuyama, Akinori Hashiguchi, Shu Wakino, Hiroshi Itoh
Published 2021-01-01

High Basolateral Glucose Increases Sodium-Glucose Cotransporter 2 and Reduces Sirtuin-1 in Renal Tubules through Glucose Transporter-2 Detection

by Hiroyuki Umino, Kazuhiro Hasegawa, Hitoshi Minakuchi, Hirokazu Muraoka, Takahisa Kawaguchi, Takeshi Kanda, Hirobumi Tokuyama, Shu Wakino, Hiroshi Itoh
Published 2018-05-01

Acute Interstitial Nephritis With Karyomegalic Epithelial Cells After Nivolumab Treatment—Two Case Reports

by Masaki Ryuzaki, Hirobumi Tokuyama, Kiyotaka Uchiyama, Hideaki Nakaya, Kazuhiro Hasegawa, Kazutoshi Miyashita, Kohnosuke Konishi, Akinori Hashiguchi, Shu Wakino, Hiroshi Itoh
Published 2019-06-01

A Case Report of Autosomal Dominant Polycystic Kidney Disease Under Peritoneal Dialysis With Cyst Infection and Culture-Positive Peritoneal Fluid

by Itaru Yasuda, Kazuhiro Hasegawa, Hirobumi Tokuyama, Naoki Washida, Keisuke Shinozuka, Marie Yasuda, Masaki Ryuzaki, Hidenori Urai, Shu Wakino, Hiroshi Itoh
Published 2019-04-01

Role of Nampt-Sirt6 Axis in Renal Proximal Tubules in Extracellular Matrix Deposition in Diabetic Nephropathy

by Hirokazu Muraoka, Kazuhiro Hasegawa, Yusuke Sakamaki, Hitoshi Minakuchi, Takahisa Kawaguchi, Itaru Yasuda, Takeshi Kanda, Hirobumi Tokuyama, Shu Wakino, Hiroshi Itoh
Published 2019-04-01

Ghrelin protects against renal damages induced by angiotensin-II via an antioxidative stress mechanism in mice.

by Keiko Fujimura, Shu Wakino, Hitoshi Minakuchi, Kazuhiro Hasegawa, Koji Hosoya, Motoaki Komatsu, Yuka Kaneko, Keisuke Shinozuka, Naoki Washida, Takeshi Kanda, Hirobumi Tokuyama, Koichi Hayashi, Hiroshi Itoh
Published 2014-01-01