The HSP70 molecular chaperone is not beneficial in a mouse model of alpha-synucleinopathy.

by Derya R Shimshek, Matthias Mueller, Christoph Wiessner, Tatjana Schweizer, P Herman van der Putten
Published 2010-01-01

Altered Short-Term Synaptic Plasticity in Mice Lacking the Metabotropic Glutamate Receptor mGlu7

by Trevor J. Bushell, Gilles Sansig, Valerie J. Collett, Herman van der Putten, Graham L. Collingridge
Published 2002-01-01

Mutant huntingtin gene-dose impacts on aggregate deposition, DARPP32 expression and neuroinflammation in HdhQ150 mice.

by Douglas Young, Franziska Mayer, Nella Vidotto, Tatjana Schweizer, Ramon Berth, Dorothee Abramowski, Derya R Shimshek, P Herman van der Putten, Peter Schmid
Published 2013-01-01

Gastrin-releasing peptide signaling plays a limited and subtle role in amygdala physiology and aversive memory.

by Frederique Chaperon, Markus Fendt, Peter H Kelly, Kurt Lingenhoehl, Johannes Mosbacher, Hans-Rudolf Olpe, Peter Schmid, Christine Sturchler, Kevin H McAllister, P Herman van der Putten, Christine E Gee
Published 2012-01-01

Neuropathology in mice expressing mouse alpha-synuclein.

by Claus Rieker, Kumlesh K Dev, Katja Lehnhoff, Samuel Barbieri, Iwona Ksiazek, Sabine Kauffmann, Simone Danner, Heinrich Schell, Cindy Boden, Markus A Ruegg, Philipp J Kahle, Herman van der Putten, Derya R Shimshek
Published 2011-01-01

High LRRK2 levels fail to induce or exacerbate neuronal alpha-synucleinopathy in mouse brain.

by Martin C Herzig, Michael Bidinosti, Tatjana Schweizer, Thomas Hafner, Christine Stemmelen, Andreas Weiss, Simone Danner, Nella Vidotto, Daniela Stauffer, Carmen Barske, Franziska Mayer, Peter Schmid, Giorgio Rovelli, P Herman van der Putten, Derya R Shimshek
Published 2012-01-01

Fragments of HdhQ150 mutant huntingtin form a soluble oligomer pool that declines with aggregate deposition upon aging.

by David Marcellin, Dorothee Abramowski, Douglas Young, Jens Richter, Andreas Weiss, Audrey Marcel, Julia Maassen, Muriel Kauffmann, Miriam Bibel, Derya R Shimshek, Richard L M Faull, Gillian P Bates, Rainer R Kuhn, P Herman Van der Putten, Peter Schmid, Gregor P Lotz
Published 2012-01-01

Synapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis

by Gemma Gomez-Giro, Jonathan Arias-Fuenzalida, Javier Jarazo, Dagmar Zeuschner, Muhammad Ali, Nina Possemis, Silvia Bolognin, Rashi Halder, Christian Jäger, Willemijn F. E. Kuper, Peter M. van Hasselt, Holm Zaehres, Antonio del Sol, Herman van der Putten, Hans R. Schöler, Jens C. Schwamborn
Published 2019-12-01

HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration.

by Michal Mielcarek, Christian Landles, Andreas Weiss, Amyaouch Bradaia, Tamara Seredenina, Linda Inuabasi, Georgina F Osborne, Kristian Wadel, Chrystelle Touller, Rachel Butler, Janette Robertson, Sophie A Franklin, Donna L Smith, Larry Park, Paul A Marks, Erich E Wanker, Eric N Olson, Ruth Luthi-Carter, Herman van der Putten, Vahri Beaumont, Gillian P Bates
Published 2013-11-01