EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers

by Joanna B. Wilson, Evelyne Manet, Henri Gruffat, Pierre Busson, Marc Blondel, Robin Fahraeus
Published 2018-04-01

Methylation-dependent binding of the epstein-barr virus BZLF1 protein to viral promoters.

by Sarah J Dickerson, Yongna Xing, Amanda R Robinson, William T Seaman, Henri Gruffat, Shannon C Kenney
Published 2009-03-01

Epstein-Barr virus down-regulates tumor suppressor DOK1 expression.

by Maha Siouda, Cecilia Frecha, Rosita Accardi, Jiping Yue, Cyrille Cuenin, Henri Gruffat, Evelyne Manet, Zdenko Herceg, Bakary S Sylla, Massimo Tommasino
Published 2014-05-01

Drosophila Yemanuclein and HIRA cooperate for de novo assembly of H3.3-containing nucleosomes in the male pronucleus.

by Guillermo A Orsi, Ahmed Algazeery, Régis E Meyer, Michèle Capri, Laure M Sapey-Triomphe, Béatrice Horard, Henri Gruffat, Pierre Couble, Ounissa Aït-Ahmed, Benjamin Loppin
Published 2013-01-01

Epstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73α.

by Rosita Accardi, Ikbal Fathallah, Henri Gruffat, Giuseppe Mariggiò, Florence Le Calvez-Kelm, Catherine Voegele, Birke Bartosch, Hector Hernandez-Vargas, James McKay, Bakary S Sylla, Evelyne Manet, Massimo Tommasino
Published 2013-03-01

Viral driven epigenetic events alter the expression of cancer-related genes in Epstein-Barr-virus naturally infected Burkitt lymphoma cell lines

by Hector Hernandez-Vargas, Henri Gruffat, Marie Pierre Cros, Audrey Diederichs, Cécilia Sirand, Romina C. Vargas-Ayala, Antonin Jay, Geoffroy Durand, Florence Le Calvez-Kelm, Zdenko Herceg, Evelyne Manet, Christopher P. Wild, Massimo Tommasino, Rosita Accardi
Published 2017-07-01

The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation.

by Nannan Wu, Xuan-Nhi Nguyen, Li Wang, Romain Appourchaux, Chengfei Zhang, Baptiste Panthu, Henri Gruffat, Chloé Journo, Sandrine Alais, Juliang Qin, Na Zhang, Kevin Tartour, Frédéric Catez, Renaud Mahieux, Theophile Ohlmann, Mingyao Liu, Bing Du, Andrea Cimarelli
Published 2019-10-01

Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs.

by Kevin Tartour, Xuan-Nhi Nguyen, Romain Appourchaux, Sonia Assil, Véronique Barateau, Louis-Marie Bloyet, Julien Burlaud Gaillard, Marie-Pierre Confort, Beatriz Escudero-Perez, Henri Gruffat, Saw See Hong, Marie Moroso, Olivier Reynard, Stéphanie Reynard, Elodie Decembre, Najate Ftaich, Axel Rossi, Nannan Wu, Frédérick Arnaud, Sylvain Baize, Marlène Dreux, Denis Gerlier, Glaucia Paranhos-Baccala, Viktor Volchkov, Philippe Roingeard, Andrea Cimarelli
Published 2017-09-01