GPCR Pharmacological Profiling of Aaptamine from the Philippine Sponge <i>Stylissa</i> sp. Extends Its Therapeutic Potential for Noncommunicable Diseases

by Harmie Luyao, Hendrik Luesch, Mylene Uy
Published 2021-09-01

Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters

by Dimitris Kallifidas, Guangde Jiang, Yousong Ding, Hendrik Luesch
Published 2018-02-01

Lyngbyastatins 8–10, Elastase Inhibitors with Cyclic Depsipeptide Scaffolds Isolated from the Marine Cyanobacterium Lyngbya semiplena

by Hendrik Luesch, Valerie J. Paul, Kanchan Taori, Jason C. Kwan
Published 2009-11-01

Isolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine Cyanobacteria

by Danmeng Luo, Masteria Y. Putra, Tao Ye, Valerie J. Paul, Hendrik Luesch
Published 2019-02-01

Vicinal difluorination as a C=C surrogate: an analog of piperine with enhanced solubility, photostability, and acetylcholinesterase inhibitory activity

by Yuvixza Lizarme-Salas, Alexandra Daryl Ariawan, Ranjala Ratnayake, Hendrik Luesch, Angela Finch, Luke Hunter
Published 2020-10-01

Largazole Inhibits Ocular Angiogenesis by Modulating the Expression of VEGFR2 and p21

by Beiying Qiu, Alison Tan, Yu Zhi Tan, Qi-Yin Chen, Hendrik Luesch, Xiaomeng Wang
Published 2021-08-01

Intramolecular Modulation of Serine Protease Inhibitor Activity in a Marine Cyanobacterium with Antifeedant Properties

by Susan Matthew, Ranjala Ratnayake, Mikel A. Becerro, Raphael Ritson-Williams, Valerie J. Paul, Hendrik Luesch
Published 2010-06-01

Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer

by Fatma H. Al-Awadhi, Lilibeth A. Salvador, Brian K. Law, Valerie J. Paul, Hendrik Luesch
Published 2017-09-01

A Highly Potent Class of Halogenated Phenazine Antibacterial and Biofilm-Eradicating Agents Accessed Through a Modular Wohl-Aue Synthesis

by Hongfen Yang, Yasmeen Abouelhassan, Gena M. Burch, Dimitris Kallifidas, Guangtao Huang, Hussain Yousaf, Shouguang Jin, Hendrik Luesch, Robert W. Huigens
Published 2017-05-01

Inhibition of cotranslational translocation by apratoxin S4: Effects on oncogenic receptor tyrosine kinases and the fate of transmembrane proteins produced in the cytoplasm

by Weijing Cai, Ranjala Ratnayake, Mengxiong Wang, Qi-Yin Chen, Kevin P. Raisch, Long H. Dang, Brian K. Law, Hendrik Luesch
Published 2021-01-01

Largazole Pharmacokinetics in Rats by LC-MS/MS

by Mingming Yu, Lilibeth A. Salvador, Sherwin K. B. Sy, Yufei Tang, Ravi S. P. Singh, Qi-Yin Chen, Yanxia Liu, Jiyong Hong, Hartmut Derendorf, Hendrik Luesch
Published 2014-03-01

Can we develop effective combination antiangiogenic therapy for patients with hepatocellular carcinoma?

by Justin B. Wenger, Napoleon Santos, Yanxia Liu, Jennifer Dallas, Sukanthini Subbiah, Steven Hochwald, Emina H. Huang, Long H. Dang, Carmen J. Allegra, Hendrik Luesch, Duyen T. Dang
Published 2011-09-01