Profiling of Extracellular Small RNAs Highlights a Strong Bias towards Non-Vesicular Secretion

by Helena Sork, Mariana Conceicao, Giulia Corso, Joel Nordin, Yi Xin Fiona Lee, Kaarel Krjutskov, Jakub Orzechowski Westholm, Pieter Vader, Marie Pauwels, Roosmarijn E. Vandenbroucke, Matthew JA Wood, Samir EL Andaloussi, Imre Mäger
Published 2021-06-01

Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD

by Anna M.L. Coenen-Stass, Helena Sork, Sole Gatto, Caroline Godfrey, Amarjit Bhomra, Kaarel Krjutškov, Jonathan R. Hart, Jakub O. Westholm, Liz O’Donovan, Andreas Roos, Hanns Lochmüller, Pier Lorenzo Puri, Samir EL Andaloussi, Matthew J.A. Wood, Thomas C. Roberts
Published 2018-12-01

Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo

by Safa Bazaz, Tõnis Lehto, Rahel Tops, Olof Gissberg, Dhanu Gupta, Burcu Bestas, Jeremy Bost, Oscar P. B. Wiklander, Helena Sork, Eman M. Zaghloul, Doste R. Mamand, Mattias Hällbrink, Rannar Sillard, Osama Saher, Kariem Ezzat, C. I. Edvard Smith, Samir EL Andaloussi, Taavi Lehto
Published 2021-08-01

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency

by Helena Sork, Joel Z Nordin, Janne J Turunen, Oscar PB Wiklander, Burcu Bestas, Eman M Zaghloul, Helerin Margus, Kärt Padari, Adil D Duru, Giulia Corso, Jeremy Bost, Pieter Vader, Margus Pooga, CI Edvard Smith, Matthew JA Wood, Raymond M Schiffelers, Mattias Hällbrink, Samir EL Andaloussi
Published 2016-01-01

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

by Oscar P. B. Wiklander, Joel Z. Nordin, Aisling O'Loughlin, Ylva Gustafsson, Giulia Corso, Imre Mäger, Pieter Vader, Yi Lee, Helena Sork, Yiqi Seow, Nina Heldring, Lydia Alvarez-Erviti, CI Edvard Smith, Katarina Le Blanc, Paolo Macchiarini, Philipp Jungebluth, Matthew J. A. Wood, Samir EL Andaloussi
Published 2015-04-01