MicroRNA as Therapeutic Targets for Chronic Wound Healing

by Eoghan J. Mulholland, Nicholas Dunne, Helen O. McCarthy
Published 2017-09-01

Enhanced nanoparticle delivery exploiting tumour-responsive formulations

by Lindsey A. Bennie, Helen O. McCarthy, Jonathan A. Coulter
Published 2018-11-01

MicroRNAs in Pancreatic Cancer: biomarkers, prognostic, and therapeutic modulators

by Afra Z. Daoud, Eoghan J. Mulholland, Grace Cole, Helen O. McCarthy
Published 2019-11-01

Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?

by John Garcia, Helen S. McCarthy, Jan Herman Kuiper, James Melrose, Sally Roberts
Published 2021-01-01

Exploring the Potential of MicroRNA Let-7c as a Therapeutic for Prostate Cancer

by Eoghan J. Mulholland, William P. Green, Niamh E. Buckley, Helen O. McCarthy
Published 2019-12-01

Synthesis and Evaluation of a Thermoresponsive Degradable Chitosan-Grafted PNIPAAm Hydrogel as a “Smart” Gene Delivery System

by Monika Ziminska, Jordan J. Wilson, Emma McErlean, Nicholas Dunne, Helen O. McCarthy
Published 2020-06-01

Calcium Phosphate Nanoparticles-Based Systems for RNAi Delivery: Applications in Bone Tissue Regeneration

by Tanya J. Levingstone, Simona Herbaj, John Redmond, Helen O. McCarthy, Nicholas J. Dunne
Published 2020-01-01

Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity

by Devon E. Anderson, Brandon D. Markway, Derek Bond, Helen E. McCarthy, Brian Johnstone
Published 2016-10-01

Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat

by John Garcia, Claire Mennan, Helen S. McCarthy, Sally Roberts, James B. Richardson, Karina T. Wright
Published 2016-01-01

Combined Autologous Chondrocyte and Bone Marrow Mesenchymal Stromal Cell Implantation in the Knee: An 8-year Follow Up of Two First-In-Man Cases

by Jingsong Wang, Karina T. Wright, Jade Perry, Bernhard Tins, Timothy Hopkins, Charlotte Hulme, Helen S. McCarthy, Ashley Brown, James B. Richardson
Published 2019-07-01

Formulating RALA/Au nanocomplexes to enhance nanoparticle internalisation efficiency, sensitising prostate tumour models to radiation treatment

by Lindsey A. Bennie, Jie Feng, Christopher Emmerson, Wendy B. Hyland, Kyle B. Matchett, Helen O. McCarthy, Jonathan A. Coulter
Published 2021-09-01

Glucocorticoid Receptor Expression Predicts Good Outcome in response to Taxane-Free, Anthracycline-Based Therapy in Triple Negative Breast Cancer

by Ahmed Elkashif, Victoria Bingham, Paula Haddock, Matthew P. Humphries, Stephen McQuaid, Paul B. Mullan, Helen O. McCarthy, Niamh E. Buckley
Published 2020-01-01

Human Mesenchymal Stromal Cells Enhance Cartilage Healing in a Murine Joint Surface Injury Model

by Jade Perry, Anke J. Roelofs, Claire Mennan, Helen S. McCarthy, Alison Richmond, Susan M. Clark, Anna H. K. Riemen, Karina Wright, Cosimo De Bari, Sally Roberts
Published 2021-08-01

Systemic RALA/iNOS Nanoparticles: A Potent Gene Therapy for Metastatic Breast Cancer Coupled as a Biomarker of Treatment

by Cian M. McCrudden, John W. McBride, Joanne McCaffrey, Ahlam A. Ali, Nicholas J. Dunne, Vicky L. Kett, Jonathan A. Coulter, Tracy Robson, Helen O. McCarthy
Published 2017-03-01

The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway.

by Anita Yakkundi, Lynn McCallum, Anthony O'Kane, Hayder Dyer, Jenny Worthington, Hayley D McKeen, Lana McClements, Christopher Elliott, Helen O McCarthy, David G Hirst, Tracy Robson
Published 2013-01-01

Gene therapy with RALA/iNOS composite nanoparticles significantly enhances survival in a model of metastatic prostate cancer

by Cian M. McCrudden, John W. McBride, Joanne McCaffrey, Emma M. McErlean, Nicholas J. Dunne, Vicky L. Kett, Jonathan A. Coulter, Tracy Robson, Helen O. McCarthy
Published 2018-06-01

Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for glioblastoma multiforme

by Lynn N Jena, Lindsey A Bennie, Emma M McErlean, Sreekanth Pentlavalli, Kim Glass, James F Burrows, Vicky L Kett, Niamh E Buckley, Jonathan A Coulter, Nicholas J Dunne, Helen O McCarthy
Published 2021-05-01

Improving the Intercellular Uptake and Osteogenic Potency of Calcium Phosphate via Nanocomplexation with the RALA Peptide

by Michelle O’Doherty, Eoghan J. Mulholland, Philip Chambers, Sreekanth Pentlavalli, Monika Ziminska, Marine J. Chalanqui, Hannah M. Pauly, Binulal N. Sathy, Tammy H. Donahue, Daniel J. Kelly, Nicholas Dunne, Helen O. McCarthy
Published 2020-12-01

FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4

by Lana McClements, Stephanie Annett, Anita Yakkundi, Martin O’Rourke, Andrea Valentine, Nermeen Moustafa, Abdelrahim Alqudah, Bruno M. Simões, Fiona Furlong, Amy Short, Stuart A. McIntosh, Helen O. McCarthy, Robert B. Clarke, Tracy Robson
Published 2019-04-01

Hydrogel-forming microneedles prepared from "super swelling" polymers combined with lyophilised wafers for transdermal drug delivery.

by Ryan F Donnelly, Maelíosa T C McCrudden, Ahlam Zaid Alkilani, Eneko Larrañeta, Emma McAlister, Aaron J Courtenay, Mary-Carmel Kearney, Thakur Raghu Raj Singh, Helen O McCarthy, Victoria L Kett, Ester Caffarel-Salvador, Sharifa Al-Zahrani, A David Woolfson
Published 2014-01-01