Benzylated Dihydroflavones and Isoquinoline-Derived Alkaloids from the Bark of <i>Diclinanona calycina</i> (Annonaceae) and Their Cytotoxicities

by Emmanoel V. Costa, Liviane do N. Soares, Jamal da Silva Chaar, Valdenizia R. Silva, Luciano de S. Santos, Hector H. F. Koolen, Felipe M. A. da Silva, Josean F. Tavares, Gokhan Zengin, Milena B. P. Soares, Daniel P. Bezerra
Published 2021-06-01

Diversity of the diterpenes in the leaves of Xylopia laevigata (Annonaceae) and their cytotoxicities

by Emmanoel V. Costa, Marília F. C. Sampaio, Leociley R. A. Menezes, Lívia M. Dutra, Cinara O. S. Costa, Maria Lúcia B. Pinheiro, Felipe M. A. da Silva, Milena B. P. Soares, Daniel P. Bezerra, Andersson Barison, Hector H. F. Koolen

In vitro and in vivo growth inhibition of human acute promyelocytic leukemia HL-60 cells by Guatteria megalophylla Diels (Annonaceae) leaf essential oil

by Rafaela G.A. Costa, Talita A. da Anunciação, Morgana de S. Araujo, César A. Souza, Rosane B. Dias, Caroline B.S. Sales, Clarissa A.G. Rocha, Milena B.P. Soares, Felipe M.A. da Silva, Hector H.F. Koolen, Emmanoel V. Costa, Daniel P. Bezerra
Published 2020-02-01

Tingenone and 22-hydroxytingenone target oxidative stress through downregulation of thioredoxin, leading to DNA double-strand break and JNK/p38-mediated apoptosis in acute myeloid...

by Ana Carolina B. da C. Rodrigues, Larissa M. Bomfim, Sara P. Neves, Milena B.P. Soares, Rosane B. Dias, Ludmila F. Valverde, Clarissa A. Gurgel Rocha, Emmanoel V. Costa, Felipe M.A. da Silva, Waldireny C. Rocha, Hector H.F. Koolen, Daniel P. Bezerra
Published 2021-10-01

Antitumor Effect of the Essential Oil from the Leaves of <i>Croton</i> <i>matourensis</i> Aubl. (Euphorbiaceae)

by Emilly J. S. P. de Lima, Rafaela G. Alves, Gigliola M. A. D´Elia, Talita A. da Anunciação, Valdenizia R. Silva, Luciano de S. Santos, Milena B. P. Soares, Nállarett M. D. Cardozo, Emmanoel V. Costa, Felipe M. A. da Silva, Hector H. F. Koolen, Daniel P. Bezerra
Published 2018-11-01

ALKALOIDS FROM LEAVES OF GUATTERIA POGONOPUS (ANNONACEAE) AND THEIR CYTOTOXICITIES

by Maria de Fátima C. Santos, José Eraldo N. Fontes, Lívia M. Dutra, Larissa M. Bomfim, Cinara O. D. Costa, Valéria R. S. Moraes, Andersson Barison, Milena B. P. Soares, Felipe Moura A. da Silva, Jackson R. G. da Silva Almeida, Héctor H. F. Koolen, Daniel P. Bezerra, Emmanoel Vilaça Costa

Synthesis and Inhibition Evaluation of New Benzyltetrahydroprotoberberine Alkaloids Designed as Acetylcholinesterase Inhibitors

by Bruna R. de Lima, Juliana M. Lima, Jéssica B. Maciel, Carolina Q. Valentim, Rita de Cássia S. Nunomura, Rita de Cássia S. Nunomura, Emerson S. Lima, Hector H. F. Koolen, Afonso Duarte L de Souza, Afonso Duarte L de Souza, Maria Lúcia B. Pinheiro, Maria Lúcia B. Pinheiro, Quezia B. Cass, Felipe Moura A. da Silva
Published 2019-09-01

Essential oil from leaves of Conobea scoparioides (Cham. &amp; Schltdl.) Benth. (Plantaginaceae) causes cell death in HepG2 cells and inhibits tumor development in a xenograft mode...

by Emilly J.S.P. de Lima, Sheila S. Fontes, Mateus L. Nogueira, Valdenizia R. Silva, Luciano de S. Santos, Gigliola M.A. D’Elia, Rosane B. Dias, Caroline B.S. Sales, Clarissa A. Gurgel Rocha, Marcos A. Vannier-Santos, Milena B.P. Soares, Emmanoel V. Costa, Felipe M.A. da Silva, Hector H.F. Koolen, Daniel P. Bezerra
Published 2020-09-01

<i>Cyperus articulatus</i> L. (Cyperaceae) Rhizome Essential Oil Causes Cell Cycle Arrest in the G₂/M Phase and Cell Death in HepG2 Cells and Inhibits the Development of...

by Mateus L. Nogueira, Emilly J. S. P. de Lima, Asenate A. X. Adrião, Sheila S. Fontes, Valdenizia R. Silva, Luciano de S. Santos, Milena B. P. Soares, Rosane B. Dias, Clarissa A. Gurgel Rocha, Emmanoel V. Costa, Felipe M. A. da Silva, Marcos A. Vannier-Santos, Nállarett M. D. Cardozo, Hector H. F. Koolen, Daniel P. Bezerra
Published 2020-06-01