Article CDG—chronic kidney disease CKD—phosphomannosemutase-2 ESRD—toll-like receptor PMM2—end stage renal disease TLR—congenital disorder of glycosylation UPC—urine protein-to-creatinine ratio acute kidney failure blood clotting disorder case report child chronic kidney failure clinical article clinical trial congenital hypothyroidism creatinine blood level eczema end stage renal disease enteropathy female gastrointestinal hemorrhage gene sequence genital system hearing impairment hemodialysis hospitalization human hyperinsulinism hypoalbuminemia hypoglycemia