IgE Antibodies: From Structure to Function and Clinical Translation

by Brian J. Sutton, Anna M. Davies, Heather J. Bax, Sophia N. Karagiannis
Published 2019-02-01

IgE Antibodies against Cancer: Efficacy and Safety

by Jitesh Chauhan, Alex J. McCraw, Mano Nakamura, Gabriel Osborn, Heng Sheng Sow, Vivienne F. Cox, Chara Stavraka, Debra H. Josephs, James F. Spicer, Sophia N. Karagiannis, Heather J. Bax
Published 2020-10-01

IgE Trimers Drive SPE-7 Cytokinergic Activity

by Heather J. Bax, Holly Bowen, Rebecca L. Beavil, Raymond Chung, Malcolm Ward, Anna M. Davies, Tihomir S. Dodev, James M. McDonnell, Andrew J. Beavil, Brian J. Sutton, Hannah J. Gould
Published 2017-08-01

Filling the Antibody Pipeline in Allergy: PIPE Cloning of IgE, IgG₁ and IgG₄ against the Major Birch Pollen Allergen Bet v 1

by Verena K. Köhler, Silvia Crescioli, Judit Fazekas-Singer, Heather J. Bax, Gerhard Hofer, Christina L. Pranger, Karin Hufnagl, Rodolfo Bianchini, Sabine Flicker, Walter Keller, Sophia N. Karagiannis, Erika Jensen-Jarolim
Published 2020-08-01

Insights from IgE Immune Surveillance in Allergy and Cancer for Anti-Tumour IgE Treatments

by Alex J. McCraw, Jitesh Chauhan, Heather J. Bax, Chara Stavraka, Gabriel Osborn, Melanie Grandits, Jacobo López-Abente, Debra H. Josephs, James Spicer, Gerd K. Wagner, Sophia N. Karagiannis, Alicia Chenoweth, Silvia Crescioli
Published 2021-09-01

B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies

by Zena N. Willsmore, Robert J. Harris, Silvia Crescioli, Khuluud Hussein, Helen Kakkassery, Deepika Thapa, Anthony Cheung, Anthony Cheung, Jitesh Chauhan, Heather J. Bax, Heather J. Bax, Alicia Chenoweth, Alicia Chenoweth, Roman Laddach, Roman Laddach, Gabriel Osborn, Alexa McCraw, Ricarda M. Hoffmann, Mano Nakamura, Jenny L. Geh, Alastair MacKenzie-Ross, Ciaran Healy, Sophia Tsoka, James F. Spicer, Sophie Papa, Sophie Papa, Linda Barber, Katie E. Lacy, Sophia N. Karagiannis, Sophia N. Karagiannis
Published 2021-01-01

Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma

by Duaa O. Khair, Heather J. Bax, Heather J. Bax, Silvia Mele, Silvia Crescioli, Giulia Pellizzari, Atousa Khiabany, Mano Nakamura, Robert J. Harris, Elise French, Ricarda M. Hoffmann, Ricarda M. Hoffmann, Iwan P. Williams, Anthony Cheung, Anthony Cheung, Benjamin Thair, Charlie T. Beales, Emma Touizer, Adrian W. Signell, Nahrin L. Tasnova, James F. Spicer, Debra H. Josephs, Debra H. Josephs, Jenny L. Geh, Alastair MacKenzie Ross, Ciaran Healy, Sophie Papa, Katie E. Lacy, Sophia N. Karagiannis
Published 2019-03-01

IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural statesResearch in context

by Giulia Pellizzari, Coran Hoskin, Silvia Crescioli, Silvia Mele, Jelena Gotovina, Giulia Chiaruttini, Rodolfo Bianchini, Kristina Ilieva, Heather J. Bax, Sophie Papa, Katie E. Lacy, Erika Jensen-Jarolim, Sophia Tsoka, Debra H. Josephs, James F. Spicer, Sophia N. Karagiannis
Published 2019-05-01

In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart

by Francis Man, Alexander Koers, Panagiotis Karagiannis, Debra H. Josephs, Heather J. Bax, Amy E. Gilbert, Tihomir S. Dodev, Silvia Mele, Giulia Chiaruttini, Silvia Crescioli, Jitesh Chauhan, Julia E. Blower, Margaret S. Cooper, James Spicer, Sophia N. Karagiannis, Philip J. Blower
Published 2021-01-01

Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma

by Mano Nakamura, Heather J. Bax, Daniele Scotto, Elmira Amiri Souri, Sam Sollie, Robert J. Harris, Niklas Hammar, Goran Walldius, Anna Winship, Sharmistha Ghosh, Ana Montes, James F. Spicer, Mieke Van Hemelrijck, Debra H. Josephs, Katie E. Lacy, Sophia Tsoka, Sophia N. Karagiannis
Published 2019-06-01

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

by Mano Nakamura, Elmira Amiri Souri, Gabriel Osborn, Roman Laddach, Jitesh Chauhan, Chara Stavraka, Sara Lombardi, Anna Black, Atousa Khiabany, Duaa O. Khair, Mariangela Figini, Anna Winship, Sharmistha Ghosh, Ana Montes, James F. Spicer, Heather J. Bax, Debra H. Josephs, Katie E. Lacy, Sophia Tsoka, Sophia N. Karagiannis
Published 2020-11-01

Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome

by Heather J. Bax, Jitesh Chauhan, Chara Stavraka, Atousa Khiabany, Mano Nakamura, Giulia Pellizzari, Kristina M. Ilieva, Sara Lombardi, Hannah J. Gould, Christopher J. Corrigan, Stephen J. Till, Sidath Katugampola, Paul S. Jones, Claire Barton, Anna Winship, Sharmistha Ghosh, Ana Montes, Debra H. Josephs, James F. Spicer, Sophia N. Karagiannis
Published 2020-07-01

Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2

by Debra H Josephs, Giulia Pellizzari, Olivier Martinez, Silvia Crescioli, Robert Page, Ashley Di Meo, Silvia Mele, Giulia Chiaruttini, Jan Hoinka, Ihor Batruch, Ioannis Prassas, Melanie Grandits, Jacobo López-Abente, Eva Bugallo-Blanco, Malcolm Ward, Heather J Bax, Elise French, Anthony Cheung, Sara Lombardi, Mariangela Figini, Katie E Lacy, Eleftherios P Diamandis
Published 2021-06-01

Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields

by Kristina M. Ilieva, Kristina M. Ilieva, Judit Fazekas-Singer, Judit Fazekas-Singer, Daniela Y. Achkova, Tihomir S. Dodev, Tihomir S. Dodev, Silvia Mele, Silvia Crescioli, Heather J. Bax, Anthony Cheung, Anthony Cheung, Panagiotis Karagiannis, Panagiotis Karagiannis, Isabel Correa, Mariangela Figini, Rebecca Marlow, Debra H. Josephs, Debra H. Josephs, Andrew J. Beavil, John Maher, John Maher, John Maher, James F. Spicer, Erika Jensen-Jarolim, Erika Jensen-Jarolim, Andrew N. Tutt, Sophia N. Karagiannis, Sophia N. Karagiannis
Published 2017-09-01