Design and synthesis of a DNA-crosslinking azinomycin analogue

by Pors, Klaus, Casely-Hayford, M.A., Hartley, J.A., Patterson, Laurence H., Searcey, M.
Published 2009

Synthesis and biological evaluation of novel chloroethylaminoanthraquinones with potent cytotoxic activity against cisplatin-resistant tumor cells

by Pors, Klaus, Paniwnyk, Z., Patterson, Laurence H., Ruparelia, K.C., Hartley, J.A., Kelland, L.R.
Published 2009

Synthesis of DNA-Directed Pyrrolidinyl and Piperidinyl Confined Alkylating Chloroalkylaminoanthraquinones: Potential for Development of Tumor-Selective N-Oxides

by Patterson, Laurence H., Pors, Klaus, Shnyder, Steven D., Teesdale-Spittle, P.H., Hartley, J.A., Searcey, M., Zloh, M.
Published 2009

Fluorescent 7-Diethylaminocoumarin Pyrrolobenzodiazepine conjugates: Synthesis, DNA-Interaction, Cytotoxicity and Differential Cellular Localization.

by Wells, G., Suggitt, Marie, Coffils, M., Baig, M.A.H., Howard, P.W., Loadman, Paul M., Hartley, J.A., Jenkins, Terence C., Thurston, D.E.
Published 2010

Phase 1 Study Of A Sequence Selective Minor Groove DNA Binding Agent (SJG-136) with Pharmacokinetic and Pharmacodynamic Measurements in Patients with Advanced Solid Tumours.

by Hochhauser, Daniel, Meyer, Timothy, Spanswick, Victoria J., Wu, Jenny, Clingen, Peter H., Loadman, Paul M., Cobb, Margaret, Gumbrell, Lindsey, Begent, Richard H., Hartley, J.A., Jodrell, Duncan
Published 2010

Molecular recognition, gene modulation and biological activity of fluorescent sequence specific DNA-interacting polyamides

by Pett, L. C.
Published 2017