Comment on “Hypercholesterolemia with consumption of PFOA-laced Western diets is dependent on strain and sex of mice” by Rebholz S.L. et al. Toxicol. Rep. 2016 (3) 46–54

by Hans M.G. Princen, Marianne G. Pouwer, Elsbet J. Pieterman
Published 2016-01-01

Beneficial effects of elafibranor on NASH in E3L.CETP mice and differences between mice and men

by Anita M. van den Hoek, Lars Verschuren, Martien P. M. Caspers, Nicole Worms, Aswin L. Menke, Hans M. G. Princen
Published 2021-03-01

Differential effects of 17α-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat

by Nynke R. Koopen, Sabine M. Post, Henk Wolters, Rick Havinga, Frans Stellaard, Renze Boverhof, Folkert Kuipers, Hans M.G. Princen
Published 1999-01-01

Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice[S]

by Marianne G. Pouwer, Elsbet J. Pieterman, Nicole Worms, Nanda Keijzer, J. Wouter Jukema, Jesper Gromada, Viktoria Gusarova, Hans M.G. Princen
Published 2020-03-01

Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice.

by Danielle van Keulen, Marianne G Pouwer, Gerard Pasterkamp, Alain J van Gool, Maarten D Sollewijn Gelpke, Hans M G Princen, Dennie Tempel
Published 2018-01-01

Chronic Oral Administration of Mineral Oil Compared With Corn Oil: Effects on Gut Permeability and Plasma Inflammatory and Lipid Biomarkers

by Elsbet J. Pieterman, Hans M. G. Princen, Annica Jarke, Ralf Nilsson, Anders Cavallin, Linnéa Bergenholm, Marcus Henricsson, V. Sashi Gopaul, Rahul Agrawal, Steven E. Nissen, Eva Hurt-Camejo
Published 2021-08-01

Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice

by Anita M. van denHoek, Elsbet J. Pieterman, José W. van derHoorn, Marta Iruarrizaga‐Lejarreta, Cristina Alonso, Lars Verschuren, Tore Skjæret, Hans M.G. Princen, David A. Fraser
Published 2020-02-01

The BCR-ABL1 Inhibitors Imatinib and Ponatinib Decrease Plasma Cholesterol and Atherosclerosis, and Nilotinib and Ponatinib Activate Coagulation in a Translational Mouse Model

by Marianne G. Pouwer, Marianne G. Pouwer, Elsbet J. Pieterman, Lars Verschuren, Martien P. M. Caspers, Cornelis Kluft, Ricardo A. Garcia, Jurjan Aman, J. Wouter Jukema, Hans M. G. Princen
Published 2018-06-01

CETP does not affect triglyceride production or clearance in APOE*3-Leiden mice

by Silvia Bijland, Sjoerd A.A van den Berg, Peter J. Voshol, Anita M. van den Hoek, Hans M.G Princen, Louis M. Havekes, Patrick C.N Rensen, Ko Willems van Dijk
Published 2010-01-01

Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression

by Caroline C. van der Hoogt, Willeke de Haan, Marit Westerterp, Menno Hoekstra, Geesje M. Dallinga-Thie, Johannes A. Romijn, Hans M.G. Princen, J. Wouter Jukema, Louis M. Havekes, Patrick C.N. Rensen
Published 2007-08-01

Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin[S]

by Susan Kühnast, José W.A. van der Hoorn, Elsbet J. Pieterman, Anita M. van den Hoek, William J. Sasiela, Viktoria Gusarova, Anusch Peyman, Hans-Ludwig Schäfer, Uwe Schwahn, J. Wouter Jukema, Hans M.G. Princen
Published 2014-10-01

The APOE∗3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis

by Marianne G. Pouwer, Suvi E. Heinonen, Margareta Behrendt, Anne-Christine Andréasson, Arianne van Koppen, Aswin L. Menke, Elsbet J. Pieterman, Anita M. van den Hoek, J. Wouter Jukema, Brendan Leighton, Ann-Cathrine Jönsson-Rylander, Hans M. G. Princen
Published 2019-01-01

Anacetrapib reduces (V)LDL cholesterol by inhibition of CETP activity and reduction of plasma PCSK9[S]

by Sam J.L. van der Tuin, Susan Kühnast, Jimmy F.P. Berbée, Lars Verschuren, Elsbet J. Pieterman, Louis M. Havekes, José W.A. van der Hoorn, Patrick C.N. Rensen, J. Wouter Jukema, Hans M.G. Princen, Ko Willems van Dijk, Yanan Wang
Published 2015-11-01

PCSK9 inhibition fails to alter hepatic LDLR, circulating cholesterol, and atherosclerosis in the absence of ApoE[S]

by Brandon Ason, José W.A. van der Hoorn, Joyce Chan, Edward Lee, Elsbet J. Pieterman, Kathy Khanh Nguyen, Mei Di, Susan Shetterly, Jie Tang, Wen-Chen Yeh, Margrit Schwarz, J. Wouter Jukema, Rob Scott, Scott M. Wasserman, Hans M.G. Princen, Simon Jackson
Published 2014-11-01

Niacin Reduces Atherosclerosis Development in APOE*3Leiden.CETP Mice Mainly by Reducing NonHDL-Cholesterol.

by Susan Kühnast, Mieke C Louwe, Mattijs M Heemskerk, Elsbet J Pieterman, Jan B van Klinken, Sjoerd A A van den Berg, Johannes W A Smit, Louis M Havekes, Patrick C N Rensen, José W A van der Hoorn, Hans M G Princen, J Wouter Jukema
Published 2013-01-01

Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.

by Danielle van Keulen, Marianne G Pouwer, Valur Emilsson, Ljubica Perisic Matic, Elsbet J Pieterman, Ulf Hedin, Vilmundur Gudnason, Lori L Jennings, Kim Holmstrøm, Boye Schnack Nielsen, Gerard Pasterkamp, Jan H N Lindeman, Alain J van Gool, Maarten D Sollewijn Gelpke, Hans M G Princen, Dennie Tempel
Published 2019-01-01

Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans

by Danielle van Keulen, Danielle van Keulen, Danielle van Keulen, Danielle van Keulen, Ian D. van Koeverden, Arjan Boltjes, Hans M. G. Princen, Alain J. van Gool, Alain J. van Gool, Gert J. de Borst, Folkert W. Asselbergs, Folkert W. Asselbergs, Folkert W. Asselbergs, Dennie Tempel, Dennie Tempel, Dennie Tempel, Gerard Pasterkamp, Sander W. van der Laan
Published 2021-04-01