Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer

by Jiangang Zhao, Jiahui Li, Hans A. Schlößer, Felix Popp, Marie Christine Popp, Hakan Alakus, Karl-Walter Jauch, Christiane J. Bruns, Yue Zhao
Published 2017-01-01

Linking Cancer Stem Cell Plasticity to Therapeutic Resistance-Mechanism and Novel Therapeutic Strategies in Esophageal Cancer

by Chenghui Zhou, Ningbo Fan, Fanyu Liu, Nan Fang, Patrick S. Plum, René Thieme, Ines Gockel, Sascha Gromnitza, Axel M. Hillmer, Seung-Hun Chon, Hans A. Schlösser, Christiane J. Bruns, Yue Zhao
Published 2020-06-01

Tumor-Derived Extracellular Vesicles Inhibit Natural Killer Cell Function in Pancreatic Cancer

by Jiangang Zhao, Hans A. Schlößer, Zhefang Wang, Jie Qin, Jiahui Li, Felix Popp, Marie Christine Popp, Hakan Alakus, Seung-Hun Chon, Hinrich P. Hansen, Wolfram F. Neiss, Karl-Walter Jauch, Christiane J. Bruns, Yue Zhao
Published 2019-06-01

B cells in esophago-gastric adenocarcinoma are highly differentiated, organize in tertiary lymphoid structures and produce tumor-specific antibodies

by Hans A. Schlößer, Martin Thelen, Axel Lechner, Kerstin Wennhold, Maria A. Garcia-Marquez, Sacha I. Rothschild, Elena Staib, Thomas Zander, Dirk Beutner, Birgit Gathof, Ramona Gilles, Engin Cukuroglu, Jonathan Göke, Alexander Shimabukuro-Vornhagen, Uta Drebber, Alexander Quaas, Christiane J. Bruns, Arnulf H. Hölscher, Michael S. Von Bergwelt-Baildon
Published 2019-01-01

Tumor-associated B cells and humoral immune response in head and neck squamous cell carcinoma

by Axel Lechner, Hans A. Schlößer, Martin Thelen, Kerstin Wennhold, Sacha I. Rothschild, Ramona Gilles, Alexander Quaas, Oliver G. Siefer, Christian U. Huebbers, Engin Cukuroglu, Jonathan Göke, Axel Hillmer, Birgit Gathof, Moritz F. Meyer, Jens P. Klussmann, Alexander Shimabukuro-Vornhagen, Sebastian Theurich, Dirk Beutner, Michael von Bergwelt-Baildon
Published 2019-03-01

Cancer-specific immune evasion and substantial heterogeneity within cancer types provide evidence for personalized immunotherapy

by Martin Thelen, Kerstin Wennhold, Jonas Lehmann, Maria Garcia-Marquez, Sebastian Klein, Elena Kochen, Philipp Lohneis, Axel Lechner, Svenja Wagener-Ryczek, Patrick Sven Plum, Oscar Velazquez Camacho, David Pfister, Fabian Dörr, Matthias Heldwein, Khosro Hekmat, Dirk Beutner, Jens Peter Klussmann, Fabinshy Thangarajah, Dominik Ratiu, Wolfram Malter, Sabine Merkelbach-Bruse, Christiane Josephine Bruns, Alexander Quaas, Michael von Bergwelt-Baildon, Hans A. Schlößer
Published 2021-06-01