Inhibition of cholesterol and steroid synthesis through miR-205 target gene SQLE is an intriguing treatment strategy in various in vitro and in vivo models of prostate cancer

by C. Kalogirou, J. Linxweiler, E. Hartmann, A. Seitz, M. Puhr, M. Spahn, T. Frank, H. Marouf, M. Krebs, H. Kübler, A. Rosenwald, M. Saar, K. Junker, B. Kneitz, W. Schmitz, M. Rosenfeldt, A. Schulze
Published 2020-07-01

MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer

by C. Kalogirou, J. Linxweiler, P. Schmucker, M. T. Snaebjornsson, W. Schmitz, S. Wach, M. Krebs, E. Hartmann, M. Puhr, A. Müller, M. Spahn, A. K. Seitz, T. Frank, H. Marouf, G. Büchel, M. Eckstein, H. Kübler, M. Eilers, M. Saar, K. Junker, F. Röhrig, B. Kneitz, M. T. Rosenfeldt, A. Schulze
Published 2021-08-01