The 3' region of the chicken hypersensitive site-4 insulator has properties similar to its core and is required for full insulator activity.

by Paritha I Arumugam, Fabrizia Urbinati, Chinavenmeni S Velu, Tomoyasu Higashimoto, H Leighton Grimes, Punam Malik
Published 2009-09-01

The miR-23a~27a~24-2 microRNA cluster buffers transcription and signaling pathways during hematopoiesis.

by Jeffrey L Kurkewich, Justin Hansen, Nathan Klopfenstein, Helen Zhang, Christian Wood, Austin Boucher, Joseph Hickman, David E Muench, H Leighton Grimes, Richard Dahl
Published 2017-07-01

Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiation.

by Fukun Guo, Shuangmin Zhang, Pulak Tripathi, Jochen Mattner, James Phelan, Alyssa Sproles, Jun Mo, Marsha Wills-Karp, H Leighton Grimes, David Hildeman, Yi Zheng
Published 2011-03-01

Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation.

by Derek S Park, Afua A Akuffo, David E Muench, H Leighton Grimes, Pearlie K Epling-Burnette, Philip K Maini, Alexander R A Anderson, Michael B Bonsall
Published 2019-04-01

DoubletDecon: Deconvoluting Doublets from Single-Cell RNA-Sequencing Data

by Erica A.K. DePasquale, Daniel J. Schnell, Pieter-Jan Van Camp, Íñigo Valiente-Alandí, Burns C. Blaxall, H. Leighton Grimes, Harinder Singh, Nathan Salomonis
Published 2019-11-01

The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification

by Yi-Chien Lu, Chad Sanada, Juliana Xavier-Ferrucio, Lin Wang, Ping-Xia Zhang, H. Leighton Grimes, Meenakshi Venkatasubramanian, Kashish Chetal, Bruce Aronow, Nathan Salomonis, Diane S. Krause
Published 2018-11-01

Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.

by James D Phelan, Ingrid Saba, Hui Zeng, Christian Kosan, Malynda S Messer, H Andre Olsson, Jennifer Fraszczak, David A Hildeman, Bruce J Aronow, Tarik Möröy, H Leighton Grimes
Published 2013-01-01

Myeloid Malignancies with Chromosome 5q Deletions Acquire a Dependency on an Intrachromosomal NF-κB Gene Network

by Jing Fang, Brenden Barker, Lyndsey Bolanos, Xiaona Liu, Andres Jerez, Hideki Makishima, Susanne Christie, Xiaoting Chen, Dinesh S. Rao, H. Leighton Grimes, Kakajan Komurov, Matthew T. Weirauch, Jose A. Cancelas, Jaroslaw P. Maciejewski, Daniel T. Starczynowski
Published 2014-09-01

Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics

by Juana Serrano-Lopez, Shailaja Hegde, Sachin Kumar, Josefina Serrano, Jing Fang, Ashley M Wellendorf, Paul A Roche, Yamileth Rangel, Leolene J Carrington, Hartmut Geiger, H Leighton Grimes, Sanjiv Luther, Ivan Maillard, Joaquin Sanchez-Garcia, Daniel T Starczynowski, Jose A Cancelas
Published 2021-04-01

Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma

by Catherine Lee, Vasilisa A. Rudneva, Serap Erkek, Marc Zapatka, Lianne Q. Chau, Silvia K. Tacheva-Grigorova, Alexandra Garancher, Jessica M. Rusert, Ozlem Aksoy, Robin Lea, Helai P. Mohammad, Jianxun Wang, William A. Weiss, H. Leighton Grimes, Stefan M. Pfister, Paul A. Northcott, Robert J. Wechsler-Reya
Published 2019-01-01