<i>Trypanosoma cruzi</i> Presenilin-Like Transmembrane Aspartyl Protease: Characterization and Cellular Localization

by Guilherme C. Lechuga, Paloma Napoleão-Pêgo, Carolina C. G. Bottino, Rosa T. Pinho, David W. Provance-Jr, Salvatore G. De-Simone
Published 2020-11-01

Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against <i>Trypanosoma cruzi</i>

by Leonardo S. Lara, Guilherme C. Lechuga, Caroline dos S. Moreira, Thaís B. Santos, Vitor F. Ferreira, David R. da Rocha, Mirian C. S. Pereira
Published 2021-01-01

Role of FAK signaling in chagasic cardiac hypertrophy

by Amanda R. Tucci, Francisco O. R. de Oliveira, Jr, Guilherme C. Lechuga, Gabriel M. Oliveira, Ana Carolina Eleuterio, Liliane B. de Mesquita, Priscila S.G. Farani, Constança Britto, Otacílio C. Moreira, Mirian Claudia S. Pereira
Published 2020-09-01

Heme crystallization in a Chagas disease vector acts as a redox-protective mechanism to allow insect reproduction and parasite infection.

by Caroline M Ferreira, Renata Stiebler, Francis M Saraiva, Guilherme C Lechuga, Ana Beatriz Walter-Nuno, Saulo C Bourguignon, Marcelo S Gonzalez, Patrícia Azambuja, Ana Caroline P Gandara, Rubem F S Menna-Barreto, Gabriela O Paiva-Silva, Marcia C Paes, Marcus F Oliveira
Published 2018-07-01

SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites

by Guilherme C. Lechuga, Franklin Souza-Silva, Carolina Q. Sacramento, Monique R. O. Trugilho, Richard H. Valente, Paloma Napoleão-Pêgo, Suelen S. G. Dias, Natalia Fintelman-Rodrigues, Jairo R. Temerozo, Nicolas Carels, Carlos R. Alves, Mirian C. S. Pereira, David W. Provance, Thiago M. L. Souza, Salvatore G. De-Simone
Published 2021-08-01