Tumor cell expression of vascular endothelial growth factor receptor 2 is an adverse prognostic factor in patients with squamous cell carcinoma of the lung.

by Timothy R Holzer, Angie D Fulford, Drew M Nedderman, Tara S Umberger, Rebecca R Hozak, Adarsh Joshi, Symantha A Melemed, Laura E Benjamin, Gregory D Plowman, Andrew E Schade, Bradley L Ackermann, Robert J Konrad, Aejaz Nasir
Published 2013-01-01

Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combinat...

by Rikke B. Holmgaard, David A. Schaer, Yanxia Li, Stephen P. Castaneda, Mary Y. Murphy, Xiaohong Xu, Ivan Inigo, Julie Dobkin, Jason R. Manro, Philip W. Iversen, David Surguladze, Gerald E. Hall, Ruslan D. Novosiadly, Karim A. Benhadji, Gregory D. Plowman, Michael Kalos, Kyla E. Driscoll
Published 2018-06-01