Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies

by Alessandra Zarantonello, Henrik Pedersen, Nick S Laursen, Gregers R Andersen
Published 2021-02-01

Birth weight and risk of adiposity among adult Inuit in Greenland.

by Pernille Falberg Rønn, Lærke Steenberg Smith, Gregers Stig Andersen, Bendix Carstensen, Peter Bjerregaard, Marit Eika Jørgensen
Published 2014-01-01

Abdominal visceral and subcutaneous adipose tissue and associations with cardiometabolic risk in Inuit, Africans and Europeans: a cross-sectional study

by Gregers Stig Andersen, Niels Grarup, Torsten Lauritzen, Bendix Carstensen, Pernille Falberg Rønn, Marit Eika Jørgensen, Dirk Lund Christensen
Published 2020-09-01

Properdin oligomers adopt rigid extended conformations supporting function

by Dennis V Pedersen, Martin Nors Pedersen, Sofia MM Mazarakis, Yong Wang, Kresten Lindorff-Larsen, Lise Arleth, Gregers R Andersen
Published 2021-01-01

α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes.

by Liz Stevenson, Erik Laursen, Graeme J Cowan, Betty Bandoh, Lea Barfod, David R Cavanagh, Gregers R Andersen, Lars Hviid
Published 2015-07-01

Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System

by Nick S. Laursen, Dennis V. Pedersen, Heidi Gytz, Alessandra Zarantonello, Jens Magnus Bernth Jensen, Annette G. Hansen, Steffen Thiel, Gregers R. Andersen
Published 2020-07-01

Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement

by Jie Zhang, Lihong Song, Dennis V Pedersen, Anna Li, John D Lambris, Gregers Rom Andersen, Tom Eirik Mollnes, Ying Jie Ma, Peter Garred
Published 2020-09-01

A Single-Domain Antibody Targeting Complement Component C5 Acts as a Selective Inhibitor of the Terminal Pathway of the Complement System and Thus Functionally Mimicks the C-Termin...

by Laure Yatime, Nicolas S. Merle, Annette G. Hansen, Niels Anton Friis, Niels Anton Friis, Jakob A. Østergaard, Mette Bjerre, Lubka T. Roumenina, Steffen Thiel, Peter Kristensen, Gregers R. Andersen
Published 2018-11-01

Associations of fat mass and fat-free mass accretion in infancy with body composition and cardiometabolic risk markers at 5 years: The Ethiopian iABC birth cohort study.

by Rasmus Wibaek, Dorte Vistisen, Tsinuel Girma, Bitiya Admassu, Mubarek Abera, Alemseged Abdissa, Marit E Jørgensen, Pernille Kæstel, Kim F Michaelsen, Henrik Friis, Jonathan C K Wells, Gregers S Andersen
Published 2019-08-01

Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction

by Frederic Jabs, Melanie Plum, Nick S. Laursen, Rasmus K. Jensen, Brian Mølgaard, Michaela Miehe, Marco Mandolesi, Michèle M. Rauber, Wolfgang Pfützner, Thilo Jakob, Christian Möbs, Gregers R. Andersen, Edzard Spillner
Published 2018-01-01

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

by Dennis V. Pedersen, Trine A. F. Gadeberg, Caroline Thomas, Yong Wang, Nicolas Joram, Rasmus K. Jensen, Sofia M. M. Mazarakis, Margot Revel, Carine El Sissy, Steen V. Petersen, Kresten Lindorff-Larsen, Steffen Thiel, Nick S. Laursen, Véronique Fremeaux-Bacchi, Gregers R. Andersen
Published 2019-08-01

Phenotypic Responses to a Lifestyle Intervention Do Not Account for Inter-Individual Variability in Glucose Tolerance for Individuals at High Risk of Type 2 Diabetes

by Grainne O’Donoghue, Grainne O’Donoghue, Aileen Kennedy, Gregers S. Andersen, Bernadette Carr, Stephen Cleary, Eoin Durkan, Heidi Davis, Kristine Færch, Paula Fitzpatrick, Helena Kenny, Noel McCaffrey, Javier Monedero, Enda Murphy, John Noone, Tommi Suvitaival, Tanja Thybo, Michael Wheeler, Dorte Vistisen, John J. Nolan, John J. Nolan, Donal J. O’Gorman, Donal J. O’Gorman
Published 2019-03-01