589 Efficacy of oncolytic vaccinia virus requires infection of suppressive immune cells in the tumor microenvironment leading to their reprogramming and deletion

by Greg Delgoffe, Paolo Vignali, Kristin DePeaux, Saumendra Sarkar
Published 2020-11-01

518 Epigenetic dysfunction of terminally exhausted tumor infiltrating T cells

by Nicole Scharping, Greg Delgoffe, Paolo Vignali, Natalie Rittenhouse, Amanda Poholek, Rhodes Ford, Andrew Frisch
Published 2020-11-01

512 Terminally exhausted CD8+ T cells potentiate the tolerogenic tumor microenvironment as functional suppressors

by Nicole Scharping, Greg Delgoffe, Paolo Vignali, Kristin DePeaux, McLane Watson, Ashley Menk
Published 2020-11-01

517 Regulatory T cell functional identity is sustained by a glucose:lactate axis that is exploited in the tumor microenvironment

by Ryan Whetstone, Greg Delgoffe, Paolo Vignali, Kristin DePeaux, McLane Watson, Ashley Menk, Steven Mullet, Ronal Peralta, Stephanie Grebinoski, Natalie Rittenhouse, Amanda Poholek, Brett Morrison, Jeffrey Rothstein, Stacy Wendell
Published 2020-11-01

254 CTLA-4 blockade promotes Treg glucose metabolism and reduces Treg functional stability in glycolysis-defective tumors

by Yasin Senbabaoglu, Greg Delgoffe, Ping-Chih Ho, Arnab Ghosh, Svena Verma, McLane Watson, Inna Serganova, Ivan Cohen, Masatomo Maeda, Masahiro Shindo, Rachana Maniyar, Mayuresh Mane, Avigdor Leftin, Matthew Lubin, Myat Kyaw Ko, Mohsen Abu-Akeel, Ellen Ackerstaff, Jason Koutcher, Ronald Blasberg
Published 2020-11-01

Challenges and next steps in the advancement of immunotherapy: summary of the 2018 and 2020 National Cancer Institute workshops on cell-based immunotherapy for solid tumors

by Nirali Shah, Lili Yang, Kasia Bourcier, Antoni Ribas, Pawel Kalinski, Ke Liu, Phil Greenberg, Carl June, Marcela Maus, Steven Rosenberg, Madhav Dhodapkar, Irina Tiper, Chantale Bernatchez, Michael Hudecek, Stanley Riddell, Stephen Gottschalk, Crystal Mackall, Lisa Butterfield, Greg Delgoffe, Michael Nishimura, Terry Fry, Marc S. Ernstoff, Christopher Klebanoff, Elad Sharon, Malcolm Brenner, Cliona Rooney, Christine Brown, Marc S Ernstoff, Tonya Webb, Magdalena Thurin, Wendell Lim, David Stroncek, Catherine Bollard, Helen Chen, Cameron Turtle, Christian Hinrichs, Laura K Fogli, Rosemarie Aurigemma, Connie L Sommers, Steven Albelda, Renier Brentjens, Yvonne Chen, Laronna Colbert, Kenneth Cornetta, Jason Cristofaro, Thomas Finn, Laura K Fogli Hunter, Alyssa Galaro, Ananda Goldrath, Ray Harris, Lori Henderson, Yuxia Jia, Dan Kaufman, Bruce Levine, Lawrence Lum, Samantha Maragh, Alex Marson, Raj Puri, Jake Reder, Isabelle Riviere, Kole Roybal, Rachelle Salomon, Tal Salz, Barbra Sasu, Andrea Schietinger, Connie L. Sommers, Minkyung Song, Fyodor Urnov, Anthony Welch, Travis Young, Jason Yovandich
Published 2021-07-01