Metabolic Reprogramming in Health and Disease

by Grazia Chiellini
Published 2020-04-01

Understanding Amyloid Structures and Disease: A Continuing Challenge in Health Research

by Grazia Chiellini
Published 2021-06-01

Transthyretin Stabilization: An Emerging Strategy for the Treatment of Alzheimer’s Disease?

by Federica Saponaro, Jin Hae Kim, Grazia Chiellini
Published 2020-11-01

3-Iodothyronamine and Derivatives: New Allies Against Metabolic Syndrome?

by Grazia Rutigliano, Lavinia Bandini, Simona Sestito, Grazia Chiellini
Published 2020-03-01

Editorial: Thyroid Hormone and Metabolites: Central Versus Peripheral Effects

by Grazia Chiellini, Federica Cioffi, Rosalba Senese, Pieter de Lange
Published 2019-04-01

Collecting data through high throughput in vitro early toxicity and off-target liability assays to rapidly identify limitations of novel thyromimetics

by Massimiliano Runfola, Simona Sestito, Sheraz Gul, Grazia Chiellini, Simona Rapposelli
Published 2020-04-01

Selective Thyroid Hormone Receptor-Beta (TRβ) Agonists: New Perspectives for the Treatment of Metabolic and Neurodegenerative Disorders

by Federica Saponaro, Simona Sestito, Massimiliano Runfola, Simona Rapposelli, Simona Rapposelli, Grazia Chiellini
Published 2020-07-01

New Multitarget Approaches in the War Against Glioblastoma: A Mini-Perspective

by Simona Sestito, Massimiliano Runfola, Marco Tonelli, Grazia Chiellini, Simona Rapposelli, Simona Rapposelli
Published 2018-08-01

3-Iodothyronamine Affects Thermogenic Substrates’ Mobilization in Brown Adipocytes

by Manuela Gencarelli, Annunziatina Laurino, Elisa Landucci, Daniela Buonvicino, Costanza Mazzantini, Grazia Chiellini, Laura Raimondi
Published 2020-05-01

Diphenyl-Methane Based Thyromimetic Inhibitors for Transthyretin Amyloidosis

by Bokyung Kim, Young Ho Ko, Massimiliano Runfola, Simona Rapposelli, Gabriella Ortore, Grazia Chiellini, Jin Hae Kim
Published 2021-03-01

Lipolytic Effects of 3-Iodothyronamine (T1AM) and a Novel Thyronamine-Like Analog SG-2 through the AMPK Pathway

by Michael Rogowski, Lorenza Bellusci, Martina Sabatini, Simona Rapposelli, Shaikh M. Rahman, Grazia Chiellini, Fariba M. Assadi-Porter
Published 2019-08-01

Brain Histamine Modulates the Antidepressant-Like Effect of the 3-Iodothyroacetic Acid (TA1)

by Annunziatina Laurino, Elisa Landucci, Lorenzo Cinci, Manuela Gencarelli, Gaetano De Siena, Lorenza Bellusci, Grazia Chiellini, Laura Raimondi
Published 2019-05-01

Modulation of gene expression by 3-iodothyronamine: genetic evidence for a lipolytic pattern.

by Veronica Mariotti, Erika Melissari, Caterina Iofrida, Marco Righi, Manuela Di Russo, Riccardo Donzelli, Alessandro Saba, Sabina Frascarelli, Grazia Chiellini, Riccardo Zucchi, Silvia Pellegrini
Published 2014-01-01

Endogenous 3-Iodothyronamine (T1AM) and Synthetic Thyronamine-Like Analog SG-2 Act as Novel Pleiotropic Neuroprotective Agents through the Modulation of SIRT6

by Lorenza Bellusci, Massimiliano Runfola, Vittoria Carnicelli, Simona Sestito, Federica Fulceri, Filippo Santucci, Paola Lenzi, Francesco Fornai, Simona Rapposelli, Nicola Origlia, Riccardo Zucchi, Grazia Chiellini
Published 2020-02-01

Delivery of Thyronamines (TAMs) to the Brain: A Preliminary Study

by Nicoletta di Leo, Stefania Moscato, Marco Borso’, Simona Sestito, Beatrice Polini, Lavinia Bandini, Agostina Grillone, Matteo Battaglini, Alessandro Saba, Letizia Mattii, Gianni Ciofani, Grazia Chiellini
Published 2021-03-01

Metabolic Reprogramming by 3-Iodothyronamine (T1AM): A New Perspective to Reverse Obesity through Co-Regulation of Sirtuin 4 and 6 Expression

by Fariba M. Assadi-Porter, Hannah Reiland, Martina Sabatini, Leonardo Lorenzini, Vittoria Carnicelli, Micheal Rogowski, Ebru S. Selen Alpergin, Marco Tonelli, Sandra Ghelardoni, Alessandro Saba, Riccardo Zucchi, Grazia Chiellini
Published 2018-05-01

New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection

by Lorenza Bellusci, Annunziatina Laurino, Martina Sabatini, Simona Sestito, Paola Lenzi, Laura Raimondi, Simona Rapposelli, Francesca Biagioni, Francesco Fornai, Francesco Fornai, Alessandra Salvetti, Leonardo Rossi, Riccardo Zucchi, Grazia Chiellini
Published 2017-12-01