Zinc Levels Modulate Lifespan through Multiple Longevity Pathways in Caenorhabditis elegans.

by Jitendra Kumar, Tracy Barhydt, Anjali Awasthi, Gordon J Lithgow, David W Killilea, Pankaj Kapahi
Published 2016-01-01

Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson’s Disease

by Dmitri Leonoudakis, Anand Rane, Suzanne Angeli, Gordon J. Lithgow, Julie K. Andersen, Shankar J. Chinta
Published 2017-01-01

Dysregulated iron metabolism in C. elegans catp-6/ATP13A2 mutant impairs mitochondrial function

by Nikhita Anand, Angelina Holcom, Michael Broussalian, Minna Schmidt, Shankar J. Chinta, Gordon J. Lithgow, Julie K. Andersen, Manish Chamoli
Published 2020-06-01

Natural Genetic Variation in Yeast Reveals That NEDD4 Is a Conserved Modifier of Mutant Polyglutamine Aggregation

by Theodore W. Peters, Christopher S. Nelson, Akos A. Gerencser, Kathleen J. Dumas, Brandon Tavshanjian, Kyu Chul Chang, Gordon J. Lithgow, Robert E. Hughes
Published 2018-11-01

Polyunsaturated fatty acids and p38-MAPK link metabolic reprogramming to cytoprotective gene expression during dietary restriction

by Manish Chamoli, Anita Goyala, Syed Shamsh Tabrez, Atif Ahmed Siddiqui, Anupama Singh, Adam Antebi, Gordon J. Lithgow, Jennifer L. Watts, Arnab Mukhopadhyay
Published 2020-09-01

Vitamin D Promotes Protein Homeostasis and Longevity via the Stress Response Pathway Genes skn-1, ire-1, and xbp-1

by Karla A. Mark, Kathleen J. Dumas, Dipa Bhaumik, Birgit Schilling, Sonnet Davis, Tal Ronnen Oron, Dylan J. Sorensen, Mark Lucanic, Rachel B. Brem, Simon Melov, Arvind Ramanathan, Bradford W. Gibson, Gordon J. Lithgow
Published 2016-10-01

Longitudinal Functional Study of Murine Aging: A Resource for Future Study Designs

by Daniel S Evans, Monique N O'Leary, Ryan Murphy, Minna Schmidt, Kristin Koenig, Michael Presley, Brittany Garrett, Ha‐Neui Kim, Li Han, Emmeline C Academia, Matt J Laye, Daniel Edgar, Christopher A Zambataro, Tracey Barhydt, Colleen M Dewey, Jarrott Mayfield, Joy Wilson, Silvestre Alavez, Mark Lucanic, Brian K Kennedy, Maria Almeida, Julie K Andersen, Pankaj Kapahi, Gordon J Lithgow, Simon Melov
Published 2021-03-01

Impact of genetic background and experimental reproducibility on identifying chemical compounds with robust longevity effects

by Mark Lucanic, W. Todd Plummer, Esteban Chen, Jailynn Harke, Anna C. Foulger, Brian Onken, Anna L. Coleman-Hulbert, Kathleen J. Dumas, Suzhen Guo, Erik Johnson, Dipa Bhaumik, Jian Xue, Anna B. Crist, Michael P. Presley, Girish Harinath, Christine A. Sedore, Manish Chamoli, Shaunak Kamat, Michelle K. Chen, Suzanne Angeli, Christina Chang, John H. Willis, Daniel Edgar, Mary Anne Royal, Elizabeth A. Chao, Shobhna Patel, Theo Garrett, Carolina Ibanez-Ventoso, June Hope, Jason L Kish, Max Guo, Gordon J. Lithgow, Monica Driscoll, Patrick C. Phillips
Published 2017-02-01