Lysosomal Membrane Permeabilization is an Early Event in Sigma-2 Receptor Ligand Mediated Cell Death in Pancreatic Cancer

by Hornick John R, Vangveravong Suwanna, Spitzer Dirk, Abate Carmen, Berardi Francesco, Goedegebuure Peter, Mach Robert H, Hawkins William G
Published 2012-05-01

The novel sigma-2 receptor ligand SW43 stabilizes pancreas cancer progression in combination with gemcitabine

by Goedegebuure Peter, Spitzer Dirk, Mitchem Jonathan B, Tu Zhude, Vangveravong Suwanna, Xu Jinbin, Hornick John R, Mach Robert H, Hawkins William G
Published 2010-11-01

Sigma-2 receptor ligands potentiate conventional chemotherapies and improve survival in models of pancreatic adenocarcinoma

by Chang Katherine, Vangveravong Suwanna, Goedegebuure Peter S, Simon Peter O, McDunn Jonathan E, Kashiwagi Hiroyuki, Hotchkiss Richard S, Mach Robert H, Hawkins William G
Published 2009-03-01

Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy

by Johnston Fabian, Chang Katherine, Jones Lynne, Xu Jinbin, Goedegebuure Peter S, Simon Peter O, McDunn Jonathan E, Kashiwagi Hiroyuki, Trinkaus Kathryn, Hotchkiss Richard S, Mach Robert H, Hawkins William G
Published 2007-07-01