PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner

by Anne-Katrien Stark, Anita Chandra, Krishnendu Chakraborty, Rafeah Alam, Valentina Carbonaro, Jonathan Clark, Srividya Sriskantharajah, Glyn Bradley, Alex G. Richter, Edward Banham-Hall, Menna R. Clatworthy, Sergey Nejentsev, J. Nicole Hamblin, Edith M. Hessel, Alison M. Condliffe, Klaus Okkenhaug
Published 2018-08-01

The application of the open pharmacological concepts triple store (open PHACTS) to support drug discovery research.

by Joseline Ratnam, Barbara Zdrazil, Daniela Digles, Emiliano Cuadrado-Rodriguez, Jean-Marc Neefs, Hannah Tipney, Ronald Siebes, Andra Waagmeester, Glyn Bradley, Chau Han Chau, Lars Richter, Jose Brea, Chris T Evelo, Edgar Jacoby, Stefan Senger, Maria Isabel Loza, Gerhard F Ecker, Christine Chichester
Published 2014-01-01